Trial reportDiabetes care2021
Trial report in Diabetes care, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05934422 (Nutritional Intervention Preconception and During Pregnancy to Maintain Healthy Glucose Metabolism and Offspring Health - Child Health and Well-being Follow Up Study), which is not on this map. Cited by 41 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Nutritional Intervention Preconception and During Pregnancy to Maintain Healthy Glucose Metabolism and Offspring Health - Child Health and Well-being Follow Up Study
Who cites it
41 citing papers in PubMed, 8 syntheses or guidelines pooled it, 63 citations in OpenAlex.
- Efficacy of inositol supplementation for the prevention and treatment of gestational diabetes in pregnant women: Results from an umbrella meta-analysis.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026Pooled it
- Preconception Interventions in Women at High Risk of Developing Gestational Diabetes: A Systematic Review.Maternal and child health journal · 2026Pooled it
- Role of preconception nutrition supplements in maternal anemia and intrauterine growth: a systematic review and meta-analysis of randomized controlled trials.Systematic reviews · 2025Pooled it
- Probiotics for the prevention of gestational diabetes mellitus: A meta-analysis of randomized controlled trials.Biomolecules & biomedicine · 2024Pooled it
- Pooled it
- The Efficacy and Safety of Myo-inositol Supplementation for the Prevention of Gestational Diabetes Mellitus in Overweight and Obese Pregnant Women: A Systematic Review and Meta-Analysis.Journal of the ASEAN Federation of Endocrine Societies · 2023Pooled it
- Pooled it
- Preventive effect of probiotics supplementation on occurrence of gestational diabetes mellitus: A systematic review and meta-analysis of randomized controlled trials.Frontiers in medicine · 2022Pooled it
- Preconception dietary patterns and time-to-conception in the high-income multi-country NiPPeR study.Nutrition journal · 2026Trial
- Hemoglobin During Pregnancy Does Not Mediate the Relationship between Nutrition Supplements and Intrauterine Growth: A Secondary Data Analysis of Women First Preconception Nutrition Trial.The Journal of nutrition · 2025Trial
- Infant body composition in a randomised trial of a maternal nutritional supplement during preconception and pregnancy.World journal of pediatrics : WJP · 2025Trial
- Higher PlasmaNutrients · 2024Trial
- Maternal mood, anxiety and mental health functioning after combined myo-inositol, probiotics, micronutrient supplementation from preconception: Findings from the NiPPeR RCT.Psychiatry research · 2024Trial
- Impact of preconception and antenatal supplementation with myo-inositol, probiotics, and micronutrients on offspring BMI and weight gain over the first 2 years.BMC medicine · 2024Trial
- Trial
- Does antenatal cholecalciferol supplementation affect the mode or timing of delivery? Post hoc analyses of the MAVIDOS randomized controlled trial.Journal of public health (Oxford, England) · 2023Trial
- Elucidating the Probiotic Potential of Lactobacillus and Bifidobacterium Species in Modulating Glucose Metabolism and Inflammation in Gestational Diabetes Mellitus: A Scoping Review.Nutrition reviews · 2026Article
- Nutrition in early life, epigenetics and lifelong health - evidence from cohort and intervention studies.The Proceedings of the Nutrition Society · 2025Review
- Maternal perspectives on Multiple Micronutrient Supplementation (MMS) in Indonesia: a cross-sectional study of knowledge, attitudes, and acceptance.BMC public health · 2025Article
- Association of Periconceptional Dietary Inflammatory Index and Hypertensive Disorders of Pregnancy and Its Subtype.American journal of reproductive immunology (New York, N.Y. : 1989) · 2025Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 5 institutions in 3 countries.
Funding
Abstract
objectiveBetter preconception metabolic and nutritional health are hypothesized to promote gestational normoglycemia and reduce preterm birth, but evidence supporting improved outcomes with nutritional supplementation starting preconception is limited. RESEARCH DESIGN AND
methodsThis double-blind randomized controlled trial recruited from the community 1,729 U.K., Singapore, and New Zealand women aged 18-38 years planning conception. We investigated whether a nutritional formulation containing
resultsBetween 2015 and 2017, participants were randomized to control (
conclusionsSupplementation with
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.