Evidence map›Paper›PMID 33782054›Full record

ArticleJournal of bacteriology2021

A-Type Carrier Proteins Are Involved in [4Fe-4S] Cluster Insertion into the Radical

Muhammad Abrar Hasnat, Arkadiusz Zupok, Justyna Jadwiga Olas, Bernd Mueller-Roeber, Silke Leimkühler

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of bacteriology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Iron limitation indirectly reduces theMicrobiology spectrum · 2024
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Muhammad Abrar HasnatInstitute of Biochemistry and Biology, Department of Molecular Enzymology, University of Potsdam, Potsdam, Germany.
Arkadiusz ZupokInstitute of Biochemistry and Biology, Department of Molecular Enzymology, University of Potsdam, Potsdam, Germany.
Justyna Jadwiga OlasInstitute of Biochemistry and Biology, Department of Molecular Biology, University of Potsdam, Potsdam, Germany.
Bernd Mueller-RoeberInstitute of Biochemistry and Biology, Department of Molecular Biology, University of Potsdam, Potsdam, Germany.
Silke LeimkühlerInstitute of Biochemistry and Biology, Department of Molecular Enzymology, University of Potsdam, Potsdam, Germany.
University of Potsdam · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Iron sulfur (Fe-S) clusters are important biological cofactors present in proteins with crucial biological functions, from photosynthesis to DNA repair, gene expression, and bioenergetic processes. For the insertion of Fe-S clusters into proteins, A-type carrier proteins have been identified. So far, three of them have been characterized in detail in Escherichia coli, namely, IscA, SufA, and ErpA, which were shown to partially replace each other in their roles in [4Fe-4S] cluster insertion into specific target proteins. To further expand the knowledge of [4Fe-4S] cluster insertion into proteins, we analyzed the complex Fe-S cluster-dependent network for the synthesis of the molybdenum cofactor (Moco) and the expression of genes encoding nitrate reductase in E. coli. Our studies include the identification of the A-type carrier proteins ErpA and IscA, involved in [4Fe-4S] cluster insertion into the radical

Indexed as

Carrier ProteinsCoenzymesEscherichia coliEscherichia coli ProteinsGene Expression Regulation, BacterialIron-Sulfur ProteinsIsomerasesMetalloproteinsMolybdenum CofactorsMultigene FamilyNitrate ReductasePteridinesCarrier ProteinsCoenzymesEscherichia coli ProteinsIron-Sulfur ProteinsIsomerasesMetalloproteinsMoaA protein, E coliMolybdenum CofactorsmolybdopterinNitrate ReductasePteridinesA-type carrier proteinFNRiron-sulfur clustersMoaAMoco biosynthesismolybdenum cofactornitrate reductase

Identifiers

PMID33782054
PMCPMC8316096
OpenAlexW3151698544

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.