Evidence map›Paper›PMID 33782010›Full record

ArticleAntimicrobial agents and chemotherapy2021

Olga Lomovskaya, Debora Rubio-Aparicio, Kirk Nelson, Dongxu Sun, Ruslan Tsivkovski, Mariana Castanheira, Jill Lindley, Jeffery Loutit, Michael Dudley

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Article
  3. CombattingAntibiotics (Basel, Switzerland) · 2025
    Review
  4. In vitro activity and resistance mechanisms of novel antimicrobial agents against metallo-β-lactamase producers.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Intrinsic Antibacterial Activity of XeruborbactamAntimicrobial agents and chemotherapy · 2022
    Article
  12. Review
  13. Review
  14. Review
  15. Article
  16. Efficacy andFrontiers in cellular and infection microbiology · 2022
    Review
  17. RSC medicinal chemistry · 2021
    Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Olga LomovskayaQpex Biopharma, Inc., San Diego, California, USA olomovskaya@qpexbio.com.ORCID 0000-0001-8637-3139
Debora Rubio-AparicioQpex Biopharma, Inc., San Diego, California, USA.
Kirk NelsonQpex Biopharma, Inc., San Diego, California, USA.
Dongxu SunQpex Biopharma, Inc., San Diego, California, USA.
Ruslan TsivkovskiQpex Biopharma, Inc., San Diego, California, USA.
Mariana CastanheiraJMI Laboratories, North Liberty, Iowa, USA.ORCID 0000-0003-0126-1782
Jill LindleyJMI Laboratories, North Liberty, Iowa, USA.
Jeffery LoutitQpex Biopharma, Inc., San Diego, California, USA.
Michael DudleyQpex Biopharma, Inc., San Diego, California, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

QPX7728 is an ultrabroad-spectrum beta-lactamase inhibitor with potent inhibition of key serine and metallo beta-lactamases. QPX7728 enhances the potency of multiple beta-lactams in beta-lactamase-producing

Indexed as

Pseudomonas aeruginosaPseudomonas InfectionsAnti-Bacterial Agentsbeta-Lactamase Inhibitorsbeta-LactamasesHumansMicrobial Sensitivity TestsAnti-Bacterial Agentsbeta-Lactamase Inhibitorsbeta-Lactamasesbeta-lactamseffluxefflux pumpsOprDPseudomonas aeruginosaQPX7728

Identifiers

PMID33782010
PMCPMC8315991

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.