ReviewHeart rhythm2021
Vein of Marshall ethanol infusion in the treatment of atrial fibrillation: From concept to clinical practice.
Review in Heart rhythm, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07755072 (The Effect of Ligament of Marshall Excision During Minimally Invasive Cardiac Surgery-Coronary Artery Bypass Grafting), which is not on this map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Ligament of Marshall Excision During Minimally Invasive Cardiac Surgery-Coronary Artery Bypass Grafting (MICS-CABG) on the Prevention of Postoperative New-Onset Atrial Fibrillation: A Multicenter, Prospective, Randomized, Triple-Blinded Study
Who cites it
27 citing papers in PubMed, 37 citations in OpenAlex.
- Ethanol Infusion Into the Vein of Marshall for Atrial Fibrillation: Clinical Efficacy and Technical Limitations.Clinical cardiology · 2026Review
- Article
- A Novel Reversed U Curve Method to Facilitate Ethanol Infusion into the Vein of Marshall in Atrial Fibrillation: A Single-Center Case Series Study.Journal of cardiovascular development and disease · 2026Article
- Epicardial Pulsed Field Ablation for Bachmann Bundle-Mediated Atrial Tachycardia: Expanding Indications and Identifying Limitations.JACC. Case reports · 2026Article
- The Role of Ethanol Ablation of the Vein of Marshall in the Era of Pulsed Field Ablation.Journal of clinical medicine · 2026Review
- Long-term clinical efficacy of Marshall vein ethanol infusion combined with catheter ablation for persistent AF.Frontiers in cardiovascular medicine · 2026Article
- A Novel Intracardiac Echocardiography-Guided Approach for Vein of Marshall Ethanol Infusion in Persistent Atrial Fibrillation Ablation.Cardiovascular therapeutics · 2026Article
- The Marshall Complex in the Human Heart: Embryology, Microanatomy, Autonomic Features and Clinical Implications for Atrial Fibrillation-A State-of-the-Art Narrative Review.Journal of clinical medicine · 2025Review
- A novel technique for vein of Marshall blood sampling and its application in assessing atrial remodeling in atrial fibrillation.Clinical research in cardiology : official journal of the German Cardiac Society · 2025Article
- Complication after vein of Marshall ethanol ablation: A case of acute cardiogenic shock and death.HeartRhythm case reports · 2025Article
- Endocardial Ablation of Atrial Flutter with Involvement of the Vein of Marshall: A Case Report.Journal of clinical medicine · 2025Article
- Enhancing ablation outcomes: vein of Marshall ethanol infusion in persistent atrial fibrillation with severe left atrial enlargement.Frontiers in cardiovascular medicine · 2025Article
- Article
- Interventions for coronary sinus access with an obstructing Thebesian valve.HeartRhythm case reports · 2024Article
- Combined ethanol and radiofrequency ablation for the elimination of focal atrial tachycardia originating from the Marshall bundle.Annals of medicine and surgery (2012) · 2024Article
- Ablation Strategies for Persistent Atrial Fibrillation: Beyond the Pulmonary Veins.Journal of clinical medicine · 2024Review
- Impact of Ethanol Infusion to the Vein of Marshall in Atrial Fibrillation and Atrial Tachycardia.Journal of cardiovascular development and disease · 2024Review
- Mechanisms of Vein of Marshall-Related Tachyarrhythmias and the Impact of Ethanol Infusion.Reviews in cardiovascular medicine · 2024Review
- Angiographic assessment of vein of Marshall in atrial fibrillation: Implications for identification and cannulation.Heliyon · 2023Article
- Double-wire technique to facilitate vein of Marshall cannulation and ethanol infusion in atrial fibrillation: a case series.BMC cardiovascular disorders · 2023Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
The vein of Marshall (VOM) contains innervation, myocardial connections, and arrhythmogenic foci that make it an attractive target in catheter ablation of atrial fibrillation (AF). Additionally, it co-localizes with the mitral isthmus, which is critical to sustain perimitral flutter, and is a true atrial vein that communicates with underlying myocardium. Retrograde balloon cannulation of the VOM from the coronary sinus is feasible and allows for ethanol delivery, which results in rapid ablation of neighboring myocardium and its innervation. Here we review the body of work performed over a span of 13 years, from the inception of the technique, to its preclinical validation, to demonstration of its ablative and denervation effects, and finally to completion of a randomized clinical trial demonstrating favorable outcomes, improving rhythm control in catheter ablation of persistent AF.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.