Evidence map›Paper›PMID 33781975›Full record

Observational studyTransplantation and cellular therapy2021

Home Spirometry Telemonitoring for Early Detection of Bronchiolitis Obliterans Syndrome in Patients with Chronic Graft-versus-Host Disease.

Jane Turner, Qianchuan He, Kelsey Baker, Lisa Chung, Adrian Lazarevic-Fogelquist, Danika Bethune, Jesse Hubbard, Margaret Guerriero, Ajay Sheshadri, Karen L Syrjala and 6 more

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in Transplantation and cellular therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 3 pooled it
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 3 syntheses or guidelines pooled it, 36 citations in OpenAlex.

  1. Guideline
  2. Guideline
  3. Unsupervised home spirometryEuropean respiratory review : an official journal of the European Respiratory Society · 2023
    Pooled it
  4. Use of Home Spirometry for Steroid Tapering.Respirology case reports · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Review
  16. Observational
  17. Article
  18. Home Spirometry in Children with Cystic Fibrosis.Bioengineering (Basel, Switzerland) · 2023
    Article
  19. Airway disease in hematologic malignancies.Expert review of respiratory medicine · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 2 countries.

Jane TurnerClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington; Division of Respirology, McMaster University, Hamilton, Ontario, Canada.
Qianchuan HePublic Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington.
Kelsey BakerClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington.
Lisa ChungVaccine and Infectious Diseases Division, Fred Hutchinson Cancer Research Center, Seattle, Washington.
Adrian Lazarevic-FogelquistUniversity of Washington School of Medicine, Seattle, Washington.
Danika BethuneUniversity of Washington School of Medicine, Seattle, Washington.
Jesse HubbardClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington.
Margaret GuerrieroDivision of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Washington School of Medicine, Seattle, Washington.
Ajay SheshadriDepartment of Pulmonary Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Karen L SyrjalaClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington; Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, Washington.
Paul J MartinClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington; Division of Hematology and Oncology, Department of Medicine, University of Washington, Seattle, Washington.
Michael BoeckhClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington; Vaccine and Infectious Diseases Division, Fred Hutchinson Cancer Research Center, Seattle, Washington; Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington.
Stephanie J LeeClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington; Division of Hematology and Oncology, Department of Medicine, University of Washington, Seattle, Washington.
Ted GooleyClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington.
Mary E FlowersClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington; Division of Hematology and Oncology, Department of Medicine, University of Washington, Seattle, Washington.
Guang-Shing ChengClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Washington School of Medicine, Seattle, Washington. Electronic address: gcheng2@fredhutch.org.
Fred Hutch Cancer Center · USUniversity of Washington · USThe University of Texas MD Anderson Cancer Center · US

Funding

Translational Bioimaging Core Shared ResourceP30CA015704 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Marian Esvelt · 1985 to 2026
$296.4M
Integrating health informatics in a scalable stepped care self-management program for survivors after hematopoietic cell transplantationR01CA215134 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI BAKER, KEVIN S, MAJHAIL, NAVNEET S. · 2017 to 2022
$3.6M
Improving Survivorship Care for Adolescents and Young Adults: a Mixed Methods Study of Alignment with the National Standards for Survivorship CareU01CA246659 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI BAKER, KEVIN S · 2020 to 2025
$3.6M
Methods for Analyzing Cancer Somatic Mutation DataR01CA223498 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI HE, QIANCHUAN · 2018 to 2022
$2.0M
NCI NIH HHS P30 CA015704NCI NIH HHS R01 CA215134NCI NIH HHS R01 CA223498NCI NIH HHS U01 CA246659
6 · The paper itself

Abstract

Early detection of bronchiolitis obliterans syndrome (BOS) after allogeneic hematopoietic cell transplantation (HCT) depends on recognition of subclinical spirometric changes, which is possible only with frequent interval spirometry. We evaluated the feasibility of home monitoring of weekly spirometry via a wireless handheld device and a web monitoring portal in a cohort of high-risk patients for the detection of lung function changes preceding BOS diagnosis. In this observational study, 46 patients with chronic graft-versus-host disease or a decline in forced expiratory volume in 1 second (FEV

Indexed as

Bronchiolitis ObliteransGraft vs Host DiseaseHumansReproducibility of ResultsRetrospective StudiesSpirometryBronchiolitis obliterans syndromeChronic GVHDEarly diagnosisHandheld spirometryHome monitoringLung complications

Identifiers

PMID33781975
PMCPMC8423348
OpenAlexW3143839826

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.