Trial reportJournal of the International Society of Sports Nutrition2021
The effects of different doses of caffeine on maximal strength and strength-endurance in women habituated to caffeine.
Trial report in Journal of the International Society of Sports Nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Effects of Caffeine Supplementation on Exercise Performance in Volleyball Players: A Systematic Review and Meta-Analysis.Nutrients · 2025Pooled it
- Effect of caffeine ingestion on cycling performance: a systematic review and meta-analysis.Frontiers in nutrition · 2025Pooled it
- Efficacy of dietary supplements on sports performance outcomes: a systematic review of evidence in elite athletes.Frontiers in nutrition · 2025Pooled it
- Effects of Acute Ingestion of Caffeine Capsules on Muscle Strength and Muscle Endurance: A Systematic Review and Meta-Analysis.Nutrients · 2024Pooled it
- Can I Have My Coffee and Drink It? A Systematic Review and Meta-analysis to Determine Whether Habitual Caffeine Consumption Affects the Ergogenic Effect of Caffeine.Sports medicine (Auckland, N.Z.) · 2022Pooled it
- Ergogenic Effects of Acute Caffeine Intake on Muscular Endurance and Muscular Strength in Women: A Meta-Analysis.International journal of environmental research and public health · 2021Pooled it
- The Acute Effects of Caffeine Supplementation on Anaerobic Performance and Functional Strength in Female Soccer Players.Nutrients · 2025Trial
- Effects of an Acute High Dose of Caffeine on Physiological Responses and Performance During a Strength-Focused CrossFitNutrients · 2025Trial
- Effects of Caffeinated Chewing Gum on Ice Hockey Performance after Jet Lag Intervention: Double-Blind Crossover Trial.Nutrients · 2024Trial
- Trial
- Effect of isolated and combined ingestion of caffeine and citrulline malate on resistance exercise and jumping performance: a randomized double-blind placebo-controlled crossover study.European journal of nutrition · 2023Trial
- The Effect of Caffeinated Chewing Gum on Volleyball-Specific Skills and Physical Performance in Volleyball Players.Nutrients · 2022Trial
- Acute effects of two caffeine doses on bar velocity during the bench press exercise among women habituated to caffeine: a randomized, crossover, double-blind study involving control and placebo conditions.European journal of nutrition · 2022Trial
- Preliminary Research towards Acute Effects of Different Doses of Caffeine on Strength-Power Performance in Highly Trained Judo Athletes.International journal of environmental research and public health · 2022Trial
- The Dose-Effects of Caffeine on Lower Body Maximal Strength, Muscular Endurance, and Rating of Perceived Exertion in Strength-Trained Females.Nutrients · 2021Trial
- High-Dose Caffeine Mouth Rinse Is an Effective Strategy for Isokinetic Strength Generation in Soccer Players.Journal of human kinetics · 2026Article
- Caffeinated chewing gum enhances maximal strength and muscular endurance during bench press and back squat exercises in resistance-trained men.Frontiers in nutrition · 2025Article
- Use of caffeine in 19,660 randomly selected U.S. adults: the role of overweight and obesity.Frontiers in nutrition · 2025Article
- Association of serum metabolites with frailty phenotype and its components: a cross-sectional case-control study.Biogerontology · 2024Article
- Will Music Give Me Power? Effects of Listening to Music during Active and Passive Rest Intervals on Power Output during Resistance Exercise.Journal of functional morphology and kinesiology · 2024Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
purposeThe main goal of this study was to assess the acute effects of 3 and 6 mg of caffeine intake per kg of body mass (b.m.) on maximal strength and strength-endurance in women habituated to caffeine.
methodsTwenty-one healthy resistance-trained female students (23.0 ± 0.9 years, body mass: 59.0 ± 6.6 kg), with a daily caffeine intake of 5.8 ± 2.6 mg/kg/b.m. participated in a randomized, crossover, double-blind design. Each participant performed three experimental sessions after ingesting either a placebo (PLAC) or 3 mg/kg/b.m. (CAF-3) and 6 mg/kg/b.m. (CAF-6) of caffeine. In each experimental session, the participants underwent a 1RM test and a strength-endurance test at 50 %1RM in the bench press exercise. Maximal load was measured in the 1RM test and the time under tension, number of preformed repetitions, power output and bar velocity were registered in the strength-endurance test.
resultsThe one-way ANOVA showed a main effect of caffeine on 1RM bench press performance (F = 14.74; p < 0.01). In comparison to the PLAC (40.48 ± 9.21 kg), CAF-3 (41.68 ± 8.98 kg; p = 0.01) and CAF-6 (42.98 ± 8.79 kg; p < 0.01) increased 1RM bench press test results. There was also a significant increase in 1RM for CAF-6 when compared to CAF-3 (p < 0.01). There was a main effect of caffeine on time under tension during the strength-endurance test (F = 13.09; p < 0.01). In comparison to the PLAC (53.52 ± 11.44 s), CAF-6 (61.76 ± 15.39 s; p < 0.01) significantly increased the time under tension during the maximal strength-endurance test.
conclusionAn acute dose of 3-to-6 mg/kg/b.m. of caffeine improves maximum strength. However, these doses of caffeine had minimal ergogenic effect on strength-endurance performance in women habituated to caffeine.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.