ArticleWorld journal of surgical oncology2021
Significance of frailty in prognosis after surgery in patients with pancreatic ductal adenocarcinoma.
Article in World journal of surgical oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Impact of frailty on outcomes of pancreatic surgery: a systematic review and meta-analysis.Frontiers in nutrition · 2026Pooled it
- Prevalence and Impact of Frailty in Pancreatic Cancer: A Systematic Review and Meta-Analysis Based on 35,191 Patients.Annals of surgical oncology · 2024Pooled it
- The Clinical Frailty Scale (CFS) employment in the frailty assessment of patients suffering from Non-Communicable Diseases (NCDs): A systematic review.Frontiers in medicine · 2022Pooled it
- Frailty in older patients with cancer in Vietnam.BMC geriatrics · 2026Observational
- Frailty, nutritional status, and inflammation as determinants of chemotherapy delivery and outcomes in pancreatic cancer patients receiving gemcitabine plus nab-paclitaxel.Frontiers in oncology · 2026Article
- Survival Analysis of 4 Different Age Groups of Pancreatic Ductal Adenocarcinoma After Radical Resection From Retrospective Multi-Center Analysis (YPB-003).Cancer medicine · 2025Article
- Impairment of perioperative activities of daily living is associated with poor prognosis following pancreatectomy for pancreatic cancer.Langenbeck's archives of surgery · 2024Article
- Differences in Pretreatment Frailty Across Gastrointestinal Cancers in Older Adults: Results From the Cancer and Aging Resilience Evaluation Registry.JCO oncology practice · 2022Article
- Preoperative nutrition and exercise intervention in frailty patients with gastric cancer undergoing gastrectomy.International journal of clinical oncology · 2022Article
- Short- and Long-Term Outcomes of Pancreatic Cancer Resection in Elderly Patients: A Nationwide Analysis.Annals of surgical oncology · 2022Article
- The Prevalence and the Impact of Frailty in Hepato-Biliary Pancreatic Cancers: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2022Article
- Prognosis and survival analysis of patients with pancreatic cancer: retrospective experience of a single institution.World journal of surgical oncology · 2022Article
- Stromal tumor-infiltrating lymphocytes level as a prognostic factor for resected intrahepatic cholangiocarcinoma and its prediction by apparent diffusion coefficient.International journal of clinical oncology · 2021Article
- Hospital Frailty Risk Score Is Independently Associated with Mortality and Encephalopathy in Hospitalized Patients with Hepatocellular Carcinoma.Biomedicines · 2021Article
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9 authors.
Funding
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Abstract
backgroundFrailty is an important consideration for older patients undergoing surgery. We aimed to investigate whether frailty could be a prognostic factor in patients with pancreatic ductal adenocarcinoma who underwent pancreatic resection.
methodsOne hundred and twenty patients who underwent pancreatic resection for pancreatic ductal adenocarcinoma were enrolled. Frailty was defined as a clinical frailty scale score ≥4. Patients were divided into frailty (n = 29) and non-frailty (n=91) groups, and clinicopathological factors were compared between the two groups.
resultsThe frailty group showed an older age, lower serum albumin concentration, lower prognostic nutritional index, larger tumor diameter, and higher rate of lymph node metastasis than the non-frailty group (p < 0.05). Neutrophil-lymphocyte ratio and modified Glasgow prognostic score tended to be higher in the frailty group. Cancer-specific and disease-free survival rates were significantly poor in the frailty group (p < 0.05). With a multivariate analysis, frailty was an independent prognostic factor of cancer-specific survival.
conclusionsFrailty can predict the prognosis of patients with pancreatic ductal adenocarcinoma who undergo pancreatic resection.
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