Evidence map›Paper›PMID 33781118›Full record

SynthesisInnovations (Philadelphia, Pa.)

Minimally Invasive Versus Sternotomy for Mitral Surgery in the Elderly: A Systematic Review and Meta-Analysis.

Ali Hage, Fadi Hage, Hussein Al-Amodi, Suruchi Gupta, Stefania I Papatheodorou, Robert Hawkins, Gorav Ailawadi, Murray A Mittleman, Michael W A Chu

Open access · hybridAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Innovations (Philadelphia, Pa.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Anaesthesia for Minimally Invasive Cardiac Surgery.Journal of cardiovascular development and disease · 2023
    Review
  10. An international survey-based assessment of minimally invasive mitral valve surgery.Interdisciplinary cardiovascular and thoracic surgery · 2023
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Ali Hage622170384 Western University, London, ON, Canada.
Fadi Hage622170384 Western University, London, ON, Canada.
Hussein Al-Amodi622170384 Western University, London, ON, Canada.
Suruchi Gupta1857 Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Stefania I Papatheodorou1857 Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Robert Hawkins235821614 University of Virginia, Charlottesville, VA, USA.
Gorav Ailawadi235821614 University of Virginia, Charlottesville, VA, USA.
Murray A Mittleman1857 Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Michael W A Chu622170384 Western University, London, ON, Canada.
Western University · CAHarvard University · USUniversity of Virginia · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe safety of minimally invasive mitral valve surgery (MIMVS) in elderly patients is still debated. Our objective was to perform a systematic review and meta-analysis of studies comparing MIMVS with conventional sternotomy (CS) in elderly patients (≥65 years old).

methodsWe searched PubMed, EMBASE, Web of Science, clinicaltrials.gov, and Cochrane Central Register of Controlled Trials for trials and observational studies comparing MIMVS with CS in patients ≥65 years old presenting for mitral valve surgery. We performed a random-effects meta-analysis of all outcomes.

resultsThe MIMVS group had lower odds of acute renal failure (odds ratio [OR] 0.27; 95% CI 0.10 to 0.78), prolonged intubation (>48 h; OR 0.47; 95% CI 0.31 to 0.70), less blood product transfusion (weighted mean difference [WMD] -0.82 units; 95% CI -1.29 to -0.34 units), shorter ICU length of stay (LOS; WMD -2.57 days; 95% CI -3.24 to -1.90 days) and hospital LOS (WMD -4.06 days; 95% CI -5.19 to -2.94 days). There were no significant differences in the odds of mortality, stroke, respiratory infection, reoperation for bleeding, and postoperative atrial fibrillation. MIMVS was associated with longer cross-clamp (WMD 11.8 min; 95% CI 3.5 to 20.1 min) and cardiopulmonary bypass times (WMD 23.0 min; 95% CI 10.4 to 35.6 min).

conclusionsMIMVS in elderly patients is associated with lower postoperative complications, blood transfusion, shorter ICU, and hospital LOS, and longer cross-clamp and bypass times.

Indexed as

Cardiac Surgical ProceduresSternotomyAgedHumansLength of StayMinimally Invasive Surgical ProceduresMitral ValvePostoperative ComplicationsTreatment Outcomemeta-analysisminimally invasivemitral surgery

Identifiers

PMID33781118
PMCPMC8414825
OpenAlexW3150948960

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.