ArticleEarly intervention in psychiatry2022
The First Episode Rapid Early Intervention for Eating Disorders - Upscaled study: Clinical outcomes.
Article in Early intervention in psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.
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Who cites it
51 citing papers in PubMed, 100 citations in OpenAlex.
- Brief Cognitive Analytic Therapy (CAT)-Informed Reformulation for Young People With Eating Disorders: A Case Series.Clinical psychology & psychotherapyTrial
- Towards a neurobiology of early intervention: the importance of critical periods for preventive psychiatry and youth mental health.Molecular psychiatry · 2026Review
- 'You Can Be Simultaneously Powerful and Marginalised at the Same Time in Different Ways'. An Intersectional Examination of Barriers and Facilitators of Help-Seeking for Eating Disorders by People From Under-Served Groups.European eating disorders review : the journal of the Eating Disorders Association · 2026Article
- Family Therapy for Anorexia Nervosa With Emerging Adults: A Retrospective Case Series in Routine Clinical Care.European eating disorders review : the journal of the Eating Disorders Association · 2026Article
- Clinical characteristics linked to persistent and emerging eating disorder risk trajectories in young people seeking mental health care.European child & adolescent psychiatry · 2026Article
- How can community pharmacists support people living with eating disorders? identifying evidence gaps and practice opportunities in Australia.Journal of eating disorders · 2026Article
- "We're on the journey now together": a qualitative examination of "close others'" perspectives on barriers and facilitators to help-seeking for eating disorders.Journal of eating disorders · 2026Article
- Mind the gap: parental perspectives on mental health service transitions for young adults with anorexia nervosa.Journal of eating disorders · 2026Article
- Predictors of Treatment Outcome in an Early Intervention Eating Disorder Sample.The International journal of eating disorders · 2026Article
- Duration of Untreated Eating Disorder and Prodrome in Young People: Characteristics and Relationship to Early Outcomes.Early intervention in psychiatry · 2026Article
- Evaluating the Impact of Eating Disorder Early Intervention on Young People's Work, Education and Social Functioning.European eating disorders review : the journal of the Eating Disorders Association · 2026Article
- Parental engagement in an early intervention program for anorexia nervosa: a qualitative study.European child & adolescent psychiatry · 2026Article
- Recent Innovations in Eating Disorder Prevention and Early Intervention.Current psychiatry reports · 2025Review
- Generating Priorities in Eating Disorder Research: Recommendations from Canadian Young Adults and Caregivers.Journal of the Canadian Academy of Child and Adolescent Psychiatry = Journal de l'Academie canadienne de psychiatrie de l'enfant et de l'adolescent · 2025Article
- Recent Advances and Future Directions in Eating Disorder Treatments for Emerging Adults.Current psychiatry reports · 2025Review
- Clinician Experiences with Adolescents with Comorbid Chronic Pain and Eating Disorders.Journal of clinical medicine · 2025Article
- The feasibility, acceptability and clinical impact of a guided self-help mobile intervention (INTERconNEcT-EDs) for individuals with eating disorders: protocol for two multicenter randomized controlled trials.Journal of eating disorders · 2025Article
- Staying on course with early intervention for eating disorders: beware of dilution and drift. Comment on Downs, J. 'Redefining prevention and early intervention to include longstanding and severe eating disorders'.Journal of eating disorders · 2025Article
- The continuing impact of COVID-19 on eating disorder early intervention services in England: An investigation of referral numbers and presentation characteristics.European psychiatry : the journal of the Association of European Psychiatrists · 2025Article
- Service models in eating disorders: a scoping review.Journal of eating disorders · 2025Review
Corrections and comments
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Authors and funding
18 authors at 7 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFirst Episode Rapid Early Intervention for Eating Disorders (FREED) is a service model and care pathway for emerging adults aged 16 to 25-years with a recent onset eating disorder (ED) of <3 years. A previous single-site study suggests that FREED significantly improves clinical outcomes compared to treatment-as-usual (TAU). The present study (FREED-Up) assessed the scalability of FREED. A multi-centre quasi-experimental pre-post design was used, comparing patient outcomes before and after implementation of FREED in participating services.
methodsFREED patients (n = 278) were consecutive, prospectively ascertained referrals to four specialist ED services in England, assessed at four time points over 12 months on ED symptoms, mood, service utilization and cost. FREED patients were compared to a TAU cohort (n = 224) of similar patients, identified retrospectively from electronic patient records in participating services. All were emerging adults aged 16-25 experiencing a first episode ED of <3 years duration.
resultsOverall, FREED patients made significant and rapid clinical improvements over time. 53.2% of FREED patients with anorexia nervosa reached a healthy weight at the 12-month timepoint, compared to only 17.9% of TAU patients (X DISCUSSION: FREED is robust and scalable and is associated with substantial improvements in clinical outcomes, reduction in inpatient or day-patient admissions, and cost-savings.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.