ReviewInternational archives of allergy and immunology2021
Sensitization against Fungi in Patients with Airway Allergies over 20 Years in Germany.
Review in International archives of allergy and immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic review of outdoor airborne fungal spore seasonality across Europe and the implications for health.The Science of the total environment · 2022Pooled it
- Management and Immunotherapy for Fungal Allergy: Clinical Practice and Unmet Needs.Clinical reviews in allergy & immunology · 2026Review
- Birch rust allergy as a novel autumnal trigger of seasonal airway symptoms.The journal of allergy and clinical immunology. Global · 2026Article
- Validity of anJournal of asthma and allergy · 2026Article
- Review
- High sensitization toThe World Allergy Organization journal · 2025Article
- Prevalence and Clinical Characteristics of Severe Asthma With Fungal Sensitization in Korea.Allergy, asthma & immunology research · 2025Article
- Racial differences in odds of asthma exacerbations among Aspergillus fumigatus-sensitized adults with asthma.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2025Article
- Increased thyroxine levels of patients with allergic rhinitis.Scientific reports · 2025Article
- Dealing with mold infestation in hospitals and medical practices.GMS hygiene and infection control · 2025Article
- Conception and Optimization of Extraction-Free Loop-Mediated Isothermal Amplification Detection of Dry Rot FungusACS omega · 2024Article
- Bayesian analysis suggests independent development of sensitization to different fungal allergens.The World Allergy Organization journal · 2024Article
- Association between equine asthma and fungal elements in the tracheal wash: An environment-matched case-control study.PloS one · 2024Article
- AWMF mold guideline "Medical clinical diagnostics for indoor mold exposure" - Update 2023 AWMF Register No. 161/001.Allergologie select · 2024Article
- Fungi-sensitized individuals have unique profiles where Alt a 1 dominates promoting response to grass, ragweed and cat allergens.Frontiers in allergy · 2024Article
- Distribution characteristics and potential risks of bioaerosols during scattered farming.iScience · 2023Article
- A novel intralesional treatment with Aureobasidium for recalcitrant warts.JAAD case reports · 2023Article
- Problems Encountered Using Fungal Extracts as Test Solutions for Fungal Allergy Diagnosis.Journal of fungi (Basel, Switzerland) · 2023Review
- Novel mechanistic insights underlying fungal allergic inflammation.PLoS pathogens · 2023Review
- Serum Vitamin D Is Inversely Associated with Blood Eosinophil Count Among Adults with Allergic Asthma.Thoracic research and practice · 2023Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFungal spores are ubiquitous allergens. Severe forms of asthma are particularly highly associated with fungal sensitization. National and international asthma guidelines recommend the implementation of allergen immunotherapy if indicated. Thus, detection and treatment of relevant allergies are key components of primary care of these patients.
objectivesThe aims of the study were (i) to investigate trends in the prevalence of sensitization to twelve fungi in central Germany over the last 20 years and (ii) to dissect specific sensitization patterns among the 3 most important fungi: Aspergillus, Alternaria, and Cladosporium.
methodsThis single-center study evaluated skin prick test (SPT) results of 3,358 patients with suspected airway allergies over a period of 20 years (1998-2017).
resultsWhile 19.2% of all study patients had positive test results to at least 1 of the 3 fungi (Alternaria, Aspergillus, or Cladosporium) in the first study decade, this rate increased to 22.5% in the second decade. Slight increases in sensitization rates to almost all fungi were observed over the 20-year period. In the last decade, polysensitization to Alternaria, Aspergillus, and Cladosporium increased significantly. Sensitization to fungi is age-dependent and peaks in the age-group of 21-40 years during the second decade.
conclusionFungi are relevant allergens for perennial and seasonal allergy symptoms. We currently recommend including Aspergillus, Alternaria, and Cladosporium in the standard series of SPTs for airway allergies.
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