Evidence map›Paper›PMID 33780653›Full record

ArticleAmerican journal of respiratory cell and molecular biology2021

Bronchopulmonary Dysplasia and Pulmonary Hypertension. The Role of Smooth Muscle

Thomas M Raffay, Koby Bonilla-Fernandez, Anjum Jafri, Ramadan B Sopi, Laura A Smith, Feifei Cui, Maureen O'Reilly, Rongli Zhang, Craig A Hodges, Peter M MacFarlane and 3 more

Open access · greenAbstract read
In one paragraph

Article in American journal of respiratory cell and molecular biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 3 countries.

Thomas M RaffayDivision of Neonatology, Department of Pediatrics, and.
Koby Bonilla-FernandezDivision of Pediatric Pulmonology, Department of Pediatrics, University Hospitals Rainbow Babies & Children's Hospital and Case Western Reserve University School of Medicine, Case Western Reserve University, Cleveland, Ohio.
Anjum JafriDivision of Pediatric Pulmonology, Department of Pediatrics, University Hospitals Rainbow Babies & Children's Hospital and Case Western Reserve University School of Medicine, Case Western Reserve University, Cleveland, Ohio.
Ramadan B SopiDivision of Neonatology, Department of Pediatrics, and.
Laura A SmithDepartment of Pediatrics, Indiana University School of Medicine, Indiana University, Indianapolis, Indiana.
Feifei CuiDivision of Pediatric Pulmonology, Department of Pediatrics, University Hospitals Rainbow Babies & Children's Hospital and Case Western Reserve University School of Medicine, Case Western Reserve University, Cleveland, Ohio.
Maureen O'ReillyDivision of Neonatology, Department of Pediatrics, and.
Rongli ZhangDepartment of Medicine, Institute for Transformative Molecular Medicine, Cardiovascular Research Institute, University Hospitals Cleveland Medical Center, and.
Craig A HodgesDepartment of Genetics, Case Western Reserve University, Cleveland, Ohio; and.
Peter M MacFarlaneDivision of Neonatology, Department of Pediatrics, and.
Gail DeutschDepartment of Pathology, Seattle Children's Hospital & University of Washington, Seattle, Washington.
Richard J MartinDivision of Neonatology, Department of Pediatrics, and.
Benjamin GastonDivision of Pediatric Pulmonology, Department of Pediatrics, University Hospitals Rainbow Babies & Children's Hospital and Case Western Reserve University School of Medicine, Case Western Reserve University, Cleveland, Ohio.
Pediatrics and Genetics · USCase Western Reserve University · USRainbow Babies & Children's Hospital · USCardiovascular Institute Hospital · JPIndiana University School of MedicineSeattle Children's Hospital · US

Funding

Project 3 - Personalized cystic fibrosis treatment strategies with synergistic therapies Identified in vitro.P01HL128192 · NHLBI · INDIANA UNIVERSITY INDIANAPOLIS · PI GASTON, BENJAMIN · 2016 to 2020
$12.2M
NEURAL REGULATION OF AIRWAYS DURING POSTNATAL MATURATIONR01HL056470 · NHLBI · MAYO CLINIC ROCHESTER · PI PRAKASH, Y. S. · 1996 to 2025
$10.5M
S-nitrosoglutathione reductase and airways hyperreactivity in murine bronchopulmonary dysplasiaK08HL133459 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI RAFFAY, THOMAS MICHAEL · 2017 to 2021
$821k
NHLBI NIH HHS K08 HL133459NHLBI NIH HHS P01 HL128192NHLBI NIH HHS R01 HL056470
6 · The paper itself

Abstract

Bronchopulmonary dysplasia (BPD) is characterized by alveolar simplification, airway hyperreactivity, and pulmonary hypertension. In our BPD model, we have investigated the metabolism of the bronchodilator and pulmonary vasodilator GSNO (

Indexed as

Alcohol DehydrogenaseAnimalsBronchopulmonary DysplasiaChildChild, PreschoolFemaleHumansHypertension, PulmonaryInfantMaleMiceMice, KnockoutMuscle, Smooth, VascularMyocytes, Smooth MuscleAdh5 protein, mouseAlcohol Dehydrogenaseairway hyperreactivityalcohol dehydrogenase-5alveolarizationneonateS-nitrosoglutathione

Identifiers

PMID33780653
PMCPMC8320118
OpenAlexW3146616104

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.