Evidence map›Paper›PMID 33780603›Full record

ArticleChronic obstructive pulmonary diseases (Miami, Fla.)2021

Development of Respercise® a Digital Application for Standardizing Home Exercise in COPD Clinical Trials.

John G Yonchuk, Divya Mohan, Nathan K LeBrasseur, Ashley R George, Sally Singh, Ruth Tal-Singer

Open access · diamondAbstract read
In one paragraph

Article in Chronic obstructive pulmonary diseases (Miami, Fla.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

John G YonchukResearch and Development Technology, GlaxoSmithKline, Collegeville, Pennsylvania, United States.
Divya MohanResearch and Development, GlaxoSmithKline, Collegeville, Pennsylvania, United States.
Nathan K LeBrasseurDepartment of Physical Medicine and Rehabilitation, Mayo Clinic Rochester, Minnesota, United States.
Ashley R GeorgeBay Digital Consulting, Hertfordshire, United Kingdom.
Sally SinghDepartment of Respiratory Sciences, University of Leicester, Leicester Biomedical Research Centre, Respiratory, Leicester, United Kingdom.
Ruth Tal-SingerCOPD Foundation, Washington, DC, United States.
Mayo Clinic · USCOPD Foundation · USGlaxoSmithKline (United States) · US

Funding

GlaxoSmithKline
6 · The paper itself

Abstract

backgroundPulmonary rehabilitation (PR) is an important therapy for patients with chronic obstructive pulmonary disease (COPD), yet uptake remains low. Intervention strategies which recapitulate the benefits of PR are, therefore, needed and digital, home-based therapies present opportunity in this space. Digital therapies also potentially offer an opportunity to standardize PR in clinical trials for new COPD therapies. AIMS AND

methodsWe aimed to create a digital application (app), Respercise

resultsFeedback from clinical trial participants was positive; 97% of respondents liked the app. A total of 88% of participants reported that it was easy to fit the exercises into their daily routine, and there was over 90% adherence for entering daily step counts. Notably, on day 90 both females and males using Respercise alone demonstrated a 2.22- and 2.27-seconds improvement in time for 5-repetition sit-to-stand tests respectively, above the 1.7 second threshold that is considered clinically meaningful in COPD.

conclusionsRespercise can be successfully deployed in clinical trials, offering the opportunity for standardization of exercise in clinical trials and, with further development, could have wider reach as a home-based intervention for individuals with COPD.

Indexed as

clinical trialscopddigital applicationsexercisephysical activityusability

Identifiers

PMID33780603
PMCPMC8237981
OpenAlexW3145380787

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.