Evidence map›Paper›PMID 33780601›Full record

ArticleFEBS open bio2021

Role of p40

Yanyun Yan, Yali Li, Meili Lv, Weifen Li, Hai Ning Shi

Open access · goldAbstract read
In one paragraph

Article in FEBS open bio, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 96% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Yanyun YanHunan Provincial Key Laboratory of Animal Intestinal Function and Regulation, College of Life Sciences, Hunan Normal University, Changsha, China.
Yali LiHunan Provincial Key Laboratory of Animal Intestinal Function and Regulation, College of Life Sciences, Hunan Normal University, Changsha, China.ORCID 0000-0001-9953-4755
Meili LvSichuan University, Chengdu, China.
Weifen LiZhejiang University, Hangzhou, China.
Hai Ning ShiMucosal Immunology and Biology Research Center, Harvard Medical School, Massachusetts General Hospital, Charlestown, MA, USA.
Hunan Normal University · CNHarvard University · USSichuan University · CNZhejiang University · CN

Funding

ROLE OF DIETARY CONSTITUENTS ON GENE EXPRESSION IN INTESTINAL EPITHELIUMP30DK040561 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI CHRISTOPHER P DUGGAN · 1994 to 2026
$31.6M
Immunomodulatory effects of intestinal helminthes on mucosal immunityR01DK082427 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI SHI, HAI NING · 2010 to 2014
$1.9M
Maternal effects on immune function in the offspringR21AI121997 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI SHI, HAI NING · 2017 to 2018
$457k
NIAID NIH HHS R21 AI121997NIDDK NIH HHS P30 DK040561NIDDK NIH HHS R01 DK082427NIH HHS R01 DK082427NIH HHS R21 AI121997
6 · The paper itself

Abstract

NADPH oxidase (NOX) is a membrane-bound enzyme complex that generates reactive oxygen species (ROS). Mutations in NOX subunit genes have been implicated in the pathogenesis of inflammatory bowel disease (IBD), indicating a crucial role for ROS in regulating host immune responses. In this study, we utilize genetically deficient mice to investigate whether defects in p40

Indexed as

AnimalsChinaCitrobacter rodentiumColitisColonDisease Models, AnimalEnterobacteriaceae InfectionsFemaleImmunityInflammatory Bowel DiseasesIntestinal MucosaMiceMice, Inbred C57BLNADPH OxidasesNitric Oxide Synthase Type IIPhosphoproteinsLancl1 protein, mouseNADPH Oxidasesneutrophil cytosol factor 40KNitric Oxide Synthase Type IIPhosphoproteinsReactive Oxygen SpeciesReceptors, G-Protein-Coupledcolonic inflammationC. rodentiumIBDp40phox

Identifiers

PMID33780601
PMCPMC8091579
OpenAlexW3142116962

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.