Evidence map›Paper›PMID 33780457›Full record

ArticlePloS one2021

Oropharyngeal meningococcal carriage in children and adolescents, a single center study in Buenos Aires, Argentina.

Angela Gentile, Maria Paula Della Latta, Mercedes Bloch, Luisina Martorelli, Barbara Wisner, Cecilia Sorhouet Pereira, Mabel Regueira, Maria Del Valle Juarez, Veronica Umido, Adriana Efron

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Meningococcal Carriage in 'Men Having Sex With Men' With Pharyngeal Gonorrhoea.Frontiers in cellular and infection microbiology · 2021
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Angela GentileEpidemiology Division, Dr Ricardo Gutiérrez Children's Hospital, Buenos Aires, Argentina.ORCID 0000-0002-1072-7700
Maria Paula Della LattaEpidemiology Division, Dr Ricardo Gutiérrez Children's Hospital, Buenos Aires, Argentina.
Mercedes BlochEpidemiology Division, Dr Ricardo Gutiérrez Children's Hospital, Buenos Aires, Argentina.
Luisina MartorelliClinical Microbiology Service, INEI-ANLIS Dr. Carlos G. Malbrán, Buenos Aires, Argentina.
Barbara WisnerClinical Microbiology Service, INEI-ANLIS Dr. Carlos G. Malbrán, Buenos Aires, Argentina.
Cecilia Sorhouet PereiraClinical Microbiology Service, INEI-ANLIS Dr. Carlos G. Malbrán, Buenos Aires, Argentina.
Mabel RegueiraClinical Microbiology Service, INEI-ANLIS Dr. Carlos G. Malbrán, Buenos Aires, Argentina.ORCID 0000-0003-2869-3542
Maria Del Valle JuarezEpidemiology Division, Dr Ricardo Gutiérrez Children's Hospital, Buenos Aires, Argentina.
Veronica UmidoEpidemiology Division, Dr Ricardo Gutiérrez Children's Hospital, Buenos Aires, Argentina.
Adriana EfronClinical Microbiology Service, INEI-ANLIS Dr. Carlos G. Malbrán, Buenos Aires, Argentina.
Administración Nacional de Laboratorios e Institutos de Salud · ARHospital General de Niños Ricardo Gutierrez · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNeisseria meningitidis (Nm) pharyngeal carriage is a necessary condition for invasive disease. We present the first carriage study in children in Buenos Aires, Argentina, considering 2017 as a transition year. Aims: to assess the rate of Nm carriage, to determine genogroup, clonal complex and outer membrane protein distribution, to determine carriage risk factors by age.

methodsCross-sectional study including children 1-17 yrs, at Ricardo Gutiérrez Children's Hospital in Buenos Aires 2017. Oro-pharyngeal swabs were taken and cultured within a short time after collection. Genogroup was determined by PCR and clonal complex by MLST. Categorical variables were analyzed.

resultsA total of 1,751 children were included. Group 1: 943 children 1-9 yrs, 38 Nm were isolated; overall carriage 4.0%. Genogroup distribution: B 26.3%, W 5.3%, Y 2.6%, Z 5.3%, other groups 7.9% and capsule null (cnl) 52.6%. Participating in extracurricular activities was the only independent predictor of Nm carriage. Group 2: 808 children 10-17 yrs, 76 Nm were isolated; overall carriage 9.4%. Genogroup distribution: B 19.7%, C 5.3%, W 7.9%, Y 9.2%, Z 5.3%, other groups 7.9% and cnl 44.7%. Independent predictors of carriage: attending pubs/night clubs and passive smoking (adjusted OR: 0.55, 95%CI = 0.32-0.93; p = 0.025).

conclusionsOverall carriage was higher in 10-17 yrs. The isolates presenting the cnl locus were prevalent in both age groups and genogroup B was the second most frequent.

Indexed as

AdolescentArgentinaChildChild, PreschoolCross-Sectional StudiesFemaleHumansInfantMaleMeningococcal InfectionsMultilocus Sequence TypingNeisseria meningitidisOropharynx

Identifiers

PMID33780457
PMCPMC8006983
OpenAlexW3141219886

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.