Evidence map›Paper›PMID 33780068›Full record

ArticleChemistry (Weinheim an der Bergstrasse, Germany)2021

Lewis Acid-Catalyzed Diels-Alder Reactions: Reactivity Trends across the Periodic Table.

Pascal Vermeeren, Marco Dalla Tiezza, Michelle van Dongen, Israel Fernández, F Matthias Bickelhaupt, Trevor A Hamlin

Abstract read
In one paragraph

Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
  2. The Diels-Alder Reaction as a Mechanistic Probe for Vibrational Strong Coupling.Angewandte Chemie (International ed. in English) · 2025
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. How Bases Catalyze Diels-Alder Reactions.Chemistry (Weinheim an der Bergstrasse, Germany) · 2023
    Article
  8. Catalyst-Free Transfer Hydrogenation of Activated Alkenes Exploiting Isopropanol as the Sole and Traceless Reductant.Green chemistry : an international journal and green chemistry resource : GC · 2023
    Article
  9. Review
  10. How Ionization Catalyzes Diels-Alder Reactions.Chemistry (Weinheim an der Bergstrasse, Germany) · 2022
    Article
  11. Article
  12. Article
  13. Review
  14. Origin of asynchronicity in Diels-Alder reactions.Physical chemistry chemical physics : PCCP · 2021
    Article
  15. Article
  16. Chemical reactivity from an activation strain perspective.Chemical communications (Cambridge, England) · 2021
    Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Pascal VermeerenDepartment of Theoretical Chemistry, Amsterdam Institute of Molecular and Life Sciences (AIMMS), Amsterdam Center for Multiscale Modeling (ACMM), Vrije Universiteit Amsterdam, De Boelelaan 1083, 1081 HV, Amsterdam (The, Netherlands.ORCID http://orcid.org/0000-0002-2100-6837
Marco Dalla TiezzaDepartment of Theoretical Chemistry, Amsterdam Institute of Molecular and Life Sciences (AIMMS), Amsterdam Center for Multiscale Modeling (ACMM), Vrije Universiteit Amsterdam, De Boelelaan 1083, 1081 HV, Amsterdam (The, Netherlands.ORCID http://orcid.org/0000-0003-3442-7654
Michelle van DongenDepartment of Theoretical Chemistry, Amsterdam Institute of Molecular and Life Sciences (AIMMS), Amsterdam Center for Multiscale Modeling (ACMM), Vrije Universiteit Amsterdam, De Boelelaan 1083, 1081 HV, Amsterdam (The, Netherlands.ORCID http://orcid.org/0000-0003-0551-3393
Israel FernándezDepartamento de Química Orgánica I and Centro de Innovación en Química Avanzada (ORFEO-CINQA), Facultad de Ciencias Químicas, Universidad Complutense de Madrid, 28040, Madrid, Spain.ORCID http://orcid.org/0000-0002-0186-9774
F Matthias BickelhauptDepartment of Theoretical Chemistry, Amsterdam Institute of Molecular and Life Sciences (AIMMS), Amsterdam Center for Multiscale Modeling (ACMM), Vrije Universiteit Amsterdam, De Boelelaan 1083, 1081 HV, Amsterdam (The, Netherlands.ORCID http://orcid.org/0000-0003-4655-7747
Trevor A HamlinDepartment of Theoretical Chemistry, Amsterdam Institute of Molecular and Life Sciences (AIMMS), Amsterdam Center for Multiscale Modeling (ACMM), Vrije Universiteit Amsterdam, De Boelelaan 1083, 1081 HV, Amsterdam (The, Netherlands.ORCID http://orcid.org/0000-0002-5128-1004

Funding

Dutch Astrochemistry NetworkDutch Astrochemistry Network (DAN)Nederlandse Organisatie voor Wetenschappelijk OnderzoekNetherlands Organization for Scientific Research (NWO)Spanish MICIIN PID2019-106184GB-I00Spanish MICIIN RED2018-102387-T
6 · The paper itself

Abstract

The catalytic effect of various weakly interacting Lewis acids (LAs) across the periodic table, based on hydrogen (Group 1), pnictogen (Group 15), chalcogen (Group 16), and halogen (Group 17) bonds, on the Diels-Alder cycloaddition reaction between 1,3-butadiene and methyl acrylate was studied quantum chemically by using relativistic density functional theory. Weakly interacting LAs accelerate the Diels-Alder reaction by lowering the reaction barrier up to 3 kcal mol

Indexed as

activation strain modeldensity functional calculationsDiels-Alder reactionLewis acidsreactivity

Identifiers

PMID33780068
PMCPMC8360170

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.