Evidence map›Paper›PMID 33780038›Full record

ArticleAmerican journal of hematology2021

An effective chemotherapy-free regimen of ponatinib plus venetoclax for relapsed/refractory Philadelphia chromosome-positive acute lymphoblastic leukemia.

Nicholas J Short, Marina Konopleva, Tapan Kadia, Partow Kebriaei, Naval Daver, Xuelin Huang, Lucia Masarova, Robin Cook, Nitin Jain, Elias Jabbour and 2 more

Open access · greenAbstract readLetter
In one paragraph

Article in American journal of hematology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 34 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Review
  4. Molecularly targeted therapy and immunotherapy in leukemias.Journal of hematology & oncology · 2026
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Mitochondria and Acute Leukemia: A Clinician's Perspective.International journal of molecular sciences · 2024
    Review
  13. Review
  14. Novel Biomarkers and Molecular Targets in ALL.Current hematologic malignancy reports · 2024
    Review
  15. Article
  16. Article
  17. Ph+ ALL in 2022: is there an optimal approach?Hematology. American Society of Hematology. Education Program · 2022
    Article
  18. B-Lymphoid Blast Phase-Chronic Myeloid Leukemia: Current Therapeutics.International journal of molecular sciences · 2022
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Nicholas J ShortDepartment of Leukemia, The University of Texas - MD Anderson Cancer Center, Houston, Texas.
Marina KonoplevaDepartment of Leukemia, The University of Texas - MD Anderson Cancer Center, Houston, Texas.ORCID 0000-0002-9347-2212
Tapan KadiaDepartment of Leukemia, The University of Texas - MD Anderson Cancer Center, Houston, Texas.ORCID 0000-0002-9892-9832
Partow KebriaeiDepartment of Stem Cell Transplantation and Cellular Therapy, The University of Texas - MD Anderson Cancer Center, Houston, Texas.
Naval DaverDepartment of Leukemia, The University of Texas - MD Anderson Cancer Center, Houston, Texas.ORCID 0000-0001-7103-373X
Xuelin HuangDepartment of Biostatistics, The University of Texas - MD Anderson Cancer Center, Houston, Texas.
Lucia MasarovaDepartment of Leukemia, The University of Texas - MD Anderson Cancer Center, Houston, Texas.
Robin CookDepartment of Leukemia, The University of Texas - MD Anderson Cancer Center, Houston, Texas.
Nitin JainDepartment of Leukemia, The University of Texas - MD Anderson Cancer Center, Houston, Texas.
Elias JabbourDepartment of Leukemia, The University of Texas - MD Anderson Cancer Center, Houston, Texas.ORCID 0000-0003-4465-6119
Hagop KantarjianDepartment of Leukemia, The University of Texas - MD Anderson Cancer Center, Houston, Texas.ORCID 0000-0002-1908-3307
Farhad RavandiDepartment of Leukemia, The University of Texas - MD Anderson Cancer Center, Houston, Texas.
The University of Texas MD Anderson Cancer Center · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Fabien Delerue · 1985 to 2026
$290.8M
University of Texas M.D. Anderson Cancer SPORE-LeukemiaP50CA100632 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI SHPALL, ELIZABETH J · 2003 to 2023
$43.7M
NCI NIH HHS P30 CA016672NCI NIH HHS P50 CA100632
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAgedAntineoplastic AgentsBridged Bicyclo Compounds, HeterocyclicHumansImidazolesMiddle AgedNeoplasm Recurrence, LocalPhiladelphia ChromosomePrecursor Cell Lymphoblastic Leukemia-LymphomaPyridazinesSulfonamidesSurvival AnalysisTreatment OutcomeAntineoplastic AgentsBridged Bicyclo Compounds, HeterocyclicImidazolesponatinibPyridazinesSulfonamidesvenetoclax

Identifiers

PMID33780038
PMCPMC9278812
OpenAlexW3148075207

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.