Evidence map›Paper›PMID 33779888›Full record

ReviewBrain topography2022

Computational Models in Electroencephalography.

Katharina Glomb, Joana Cabral, Anna Cattani, Alberto Mazzoni, Ashish Raj, Benedetta Franceschiello

Abstract readReview
In one paragraph

Review in Brain topography, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

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  6. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Katharina GlombConnectomics Lab, Department of Radiology, Lausanne University Hospital and University of Lausanne (CHUV-UNIL), Lausanne, Switzerland. katharina.glomb@gmail.com.ORCID 0000-0002-4596-4386
Joana CabralLife and Health Sciences Research Institute (ICVS), University of Minho, Braga, Portugal.
Anna CattaniDepartment of Psychiatry, University of Wisconsin-Madison, Madison, USA.
Alberto MazzoniThe BioRobotics Institute, Scuola Superiore Sant'Anna, Pisa, Italy.
Ashish RajSchool of Medicine, UCSF, San Francisco, USA.
Benedetta FranceschielloDepartment of Ophthalmology, Hopital Ophthalmic Jules Gonin, FAA, Lausanne, Switzerland.

Funding

Network Modelling of Multimodal Dynamics in Alzheimer’s Disease and DementiaRF1AG062196 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI NAGARAJAN, SRIKANTAN S., RAJ, ASHISH · 2019 to 2019
$3.0M
Predictive model of spread of Parkinson's pathology using network diffusionR01NS092802 · NINDS · WEILL MEDICAL COLL OF CORNELL UNIV · PI GUPTA, AJAY, RAJ, ASHISH · 2016 to 2020
$2.8M
Understanding the dynamic interactions between tau pathology and microglia-mediated inflammation in Alzheimer's DiseaseR56AG064873 · NIA · WEILL MEDICAL COLL OF CORNELL UNIV · PI GUPTA, AJAY, RAJ, ASHISH · 2019 to 2019
$771k
NIA NIH HHS R56 AG064873NIH HHS R01NS092802NIH HHS RF1AG062196
6 · The paper itself

Abstract

Computational models lie at the intersection of basic neuroscience and healthcare applications because they allow researchers to test hypotheses in silico and predict the outcome of experiments and interactions that are very hard to test in reality. Yet, what is meant by "computational model" is understood in many different ways by researchers in different fields of neuroscience and psychology, hindering communication and collaboration. In this review, we point out the state of the art of computational modeling in Electroencephalography (EEG) and outline how these models can be used to integrate findings from electrophysiology, network-level models, and behavior. On the one hand, computational models serve to investigate the mechanisms that generate brain activity, for example measured with EEG, such as the transient emergence of oscillations at different frequency bands and/or with different spatial topographies. On the other hand, computational models serve to design experiments and test hypotheses in silico. The final purpose of computational models of EEG is to obtain a comprehensive understanding of the mechanisms that underlie the EEG signal. This is crucial for an accurate interpretation of EEG measurements that may ultimately serve in the development of novel clinical applications.

Indexed as

BrainElectroencephalographyComputer SimulationHumansModels, NeurologicalClinical applicationsComputational modelingElectroencephalographyMultiscale modeling

Identifiers

PMID33779888
PMCPMC8813814

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.