ArticleWorld journal of urology2021
Trends in urinary stone composition in 23,182 stone analyses from 2011 to 2019: a high-volume center study in China.
Article in World journal of urology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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18 citing papers in PubMed, 26 citations in OpenAlex.
- Identification of key molecules and pathways in CaOx crystal-induced renal injury based on metabolomics and proteomics.International urology and nephrology · 2026Article
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- The effects of elevated phosphate on the kidney - damaging the gatekeeper.Pflugers Archiv : European journal of physiology · 2026Review
- A study on metabolic differences between infectious and non-infectious stones in patients with urine culture positive for Proteus mirabilis.BMC urology · 2026Article
- Urinary proteins from stone formers promote calcium oxalate crystallization, growth and aggregation via oxidative modifications.Journal of advanced research · 2026Article
- Article
- The role of inflammation and ROS in CaOx kidney stones.European journal of medical research · 2025Review
- Environmental determinants in the development of kidney stone.Urolithiasis · 2025Review
- Causal association of serum vitamin D levels with urolithiasis: a bidirectional two-sample Mendelian randomization study.European journal of nutrition · 2024Article
- Characteristics of urinary stone composition among patients with urolithiasis: a retrospective study in China.BMJ open · 2024Observational
- Understanding formation processes of calcareous nephrolithiasis in renal interstitium and tubule lumen.Journal of cellular and molecular medicine · 2024Review
- Mixed stones: urinary stone composition, frequency and distribution by gender and age.Urolithiasis · 2024Article
- Theranostic roles of machine learning in clinical management of kidney stone disease.Computational and structural biotechnology journal · 2023Review
- A smartphone-based self-care application for patients with urinary tract stones: identification of information content and functional capabilities.BMC urology · 2022Article
- The impacts of metabolic syndrome on the risk of severe urolithiasis.Urolithiasis · 2022Article
- Urinary stone composition in Germany: results from 45,783 stone analyses.World journal of urology · 2022Article
- Article
- Letter to the editor regarding the article "Trends in urinary stone composition in 23,182 stone analyses from 2011 to 2019: a high-volume center study in China".World journal of urology · 2022Article
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8 authors at 2 institutions in 2 countries.
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Abstract
purposeTo evaluate the distribution and dynamic trends in constituents of urinary stones in China. MATERIALS AND
methodsThe composition of 23,182 stones were analyzed and then recorded between January 2011 and December 2019. The characteristics in terms of stone patient's gender, age and calendar year were analyzed.
resultsMost stones (22,172, 95.64%) had several crystal components, among which 40.25% (8925/22,172) were mixtures with infection components. Calcium oxalate (CaOx) and uric acid (UA) stones were more commonly encountered in men, but calcium phosphate (CaP), magnesium ammonium phosphate (MAP) and carbonate apatite (CA) stones were more prevalent in women (p < 0.05). In males, the proportion of CaOx stones increased up to the age of 40, but subsequently decreased (p < 0.001). Interestingly, females showed an inverse trend regarding CaOx stones (p < 0.001). The proportion of UA stones increased with age (p < 0.001), and CA stones most frequently were recorded at age 20-49. Over the past 9 years, UA, CA, and MAP stones increased over time, whereas there was a tendency for CaOx stones to decrease (p < 0.05).
conclusionsThe scarcity of pure stones and a certain proportion of mixtures with infection stone components (e.g., mixtures of CaOx and CA) suggest that treatment directed against a single stone component is insufficient for effective recurrence prevention. Age and gender were significant determinants of stone composition, and according to the observed chronological trends, it seems that in the future, more UA, CA and MAP stones and fewer CaOx stones may be encountered in the studied population.
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