Evidence map›Paper›PMID 33779809›Full record

ArticleClinical research in cardiology : official journal of the German Cardiac Society2021

CMR feature tracking strain patterns and their association with circulating cardiac biomarkers in patients with hypertrophic cardiomyopathy.

Ersin Cavus, Kai Muellerleile, Samuel Schellert, Jan Schneider, Enver Tahir, Celeste Chevalier, Charlotte Jahnke, Ulf K Radunski, Gerhard Adam, Paulus Kirchhof and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 33 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Ersin CavusClinic of Cardiology, University Heart and Vascular Center Hamburg Eppendorf, Martinistr.52, 20246, Hamburg, Germany. ersin.cavus@uke.de.ORCID http://orcid.org/0000-0002-5372-8690
Kai MuellerleileClinic of Cardiology, University Heart and Vascular Center Hamburg Eppendorf, Martinistr.52, 20246, Hamburg, Germany.
Samuel SchellertClinic of Cardiology, University Heart and Vascular Center Hamburg Eppendorf, Martinistr.52, 20246, Hamburg, Germany.
Jan SchneiderClinic of Cardiology, University Heart and Vascular Center Hamburg Eppendorf, Martinistr.52, 20246, Hamburg, Germany.
Enver TahirDepartment of Diagnostic and Interventional Radiology, University Hospital Hamburg Eppendorf, Hamburg, Germany.
Celeste ChevalierClinic of Cardiology, University Heart and Vascular Center Hamburg Eppendorf, Martinistr.52, 20246, Hamburg, Germany.
Charlotte JahnkeClinic of Cardiology, University Heart and Vascular Center Hamburg Eppendorf, Martinistr.52, 20246, Hamburg, Germany.
Ulf K RadunskiDepartment of Cardiology and Angiology, Regio Clinics, Elmshorn and Pinneberg, Germany.
Gerhard AdamDepartment of Diagnostic and Interventional Radiology, University Hospital Hamburg Eppendorf, Hamburg, Germany.
Paulus KirchhofClinic of Cardiology, University Heart and Vascular Center Hamburg Eppendorf, Martinistr.52, 20246, Hamburg, Germany.
Stefan BlankenbergClinic of Cardiology, University Heart and Vascular Center Hamburg Eppendorf, Martinistr.52, 20246, Hamburg, Germany.
Gunnar K LundDepartment of Diagnostic and Interventional Radiology, University Hospital Hamburg Eppendorf, Hamburg, Germany.
Maxim Avanesov *Department of Radiology, AK Segeberger Kliniken GmbH, Bad Segeberg, Germany.
Monica Patten *Clinic of Cardiology, University Heart and Vascular Center Hamburg Eppendorf, Martinistr.52, 20246, Hamburg, Germany.
University Medical Center Hamburg-Eppendorf · DEUniversität Hamburg · DERegio Kliniken · DESegeberger Kliniken · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsCMR feature tracking strain (CMR-FT) provides prognostic information. However, there is a paucity of data in hypertrophic cardiomyopathy (HCM). We sought to analyze global CMR-FT parameters in all four cardiac chambers and to assess associations with NT-proBNP and cardiac troponin T (hsTnT) in patients with HCM.

methodsThis retrospective study included 144 HCM patients and 16 healthy controls with CMR at 1.5 T. Analyses were performed on standard steady-state free precession cine (SSFP) CMR data using a commercially available software. Global left ventricular (LV) strain was assessed as longitudinal (LV

resultsWe found LV

conclusionCMR-FT reveals LV and LA dysfunction in HCM despite normal LVEF. The association between impaired LV strain and elevated NT-proBNP and hsTnT indicates a link between unapparent functional abnormalities and disease severity in HCM. Typical CMR-FT findings in patients with hypertrophic cardiomyopathy.

Indexed as

AdultBiomarkersCardiomyopathy, HypertrophicFemaleFollow-Up StudiesHeart VentriclesHumansMagnetic Resonance Imaging, CineMaleMiddle AgedMyocardial ContractionNatriuretic Peptide, BrainPeptide FragmentsPrognosisRetrospective StudiesROC CurveBiomarkersNatriuretic Peptide, BrainPeptide Fragmentspro-brain natriuretic peptide (1-76)Cardiac biomarkerCMR feature tracking strainHypertrophic cardiomyopathyStrain imaging

Identifiers

PMID33779809
PMCPMC8563550
OpenAlexW3143087508

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.