ReviewThe Journal of pharmacy and pharmacology2021
Isatis indigotica: a review of phytochemistry, pharmacological activities and clinical applications.
Review in The Journal of pharmacy and pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed.
- Hair Growth-Promoting Effect of a Horse Oil-Folium Isatidis Topical Preparation via Modulation of VEGF, TGF-β1, and β-Catenin Signaling in C57BL/6 Alopecia Mice: A Pilot Study.Current issues in molecular biology · 2026Article
- An integrated machine learning framework for TCM five-flavor classification based on E-tongue profiling and SHAP analysis.Chinese medicine · 2026Article
- Deciphering lipid biosynthesis and regulation in Isatis species through combined metabolomic and transcriptomic analysis.BMC plant biology · 2026Article
- Complete chloroplast genome data ofData in brief · 2026Article
- Bioactive Supermolecules: The Promising Assemblies Presented in Traditional Chinese Medicine.Current drug delivery · 2026Review
- The effect of endophytic bacteria on the growth, medicinal quality, and rhizosphere soil environment ofFrontiers in plant science · 2026Article
- Exogenous GABA regulates the growth traits, photosynthesis, antioxidant properties, and nitrogen metabolism inFrontiers in plant science · 2026Article
- Mechanism of action of heat-clearing and detoxifying herbs in the treatment of erosive gastritis.World journal of gastroenterology · 2025Review
- Comparative transcriptome analysis of Isatis indigotica under different precipitation conditions.Molecular biology reports · 2025Article
- Genetic Analysis and Fingerprint Construction forCurrent issues in molecular biology · 2025Article
- Identification and expression analysis of the RBOH gene family of Isatis indigotica Fort. and the potential regulation mechanism of RBOH gene on HPlant cell reports · 2025Article
- Transcriptomics and network pharmacology reveal the molecular mechanisms through which leonurine protects againstFrontiers in microbiology · 2025Article
- Integrated omics analysis of PGPR and AMF effects on soil microbiota and root metabolites inFrontiers in microbiomes · 2025Article
- Physiological and Cellular Ultrastructural Responses ofPlants (Basel, Switzerland) · 2024Article
- Inhibitory Efficacy of Main Components ofInternational journal of molecular sciences · 2024Article
- Effect of miR-17 onFrontiers in veterinary science · 2024Article
- Identifying plant-derived antiviral alkaloids as dual inhibitors of SARS-CoV-2 main protease and spike glycoprotein through computational screening.Frontiers in pharmacology · 2024Article
- Article
- Discovery of Novel Tryptanthrin Derivatives with Benzenesulfonamide Substituents as Multi-Target-Directed Ligands for the Treatment of Alzheimer's Disease.Pharmaceuticals (Basel, Switzerland) · 2023Article
- A General Strategy for the Synthesis of Truxinate Natural Products Enabled by Enantioselective [2+2] Photocycloadditions.Journal of the American Chemical Society · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
objectivesIsatis indigotica Fort. (I. indigotica) is an herbaceous plant belonging to Cruciferae family. Its leaf (IIL) and root (IIR) are commonly used in traditional Chinese medicines (TCMs) with good clinical efficacies such as clearing away heat and detoxification, cooling blood and reducing swelling. This review aimed to provide a systematic summary on the phytochemistry, pharmacology and clinical applications of I. indigotica. KEY
findingsThis plant contains alkaloids, organic acids, flavonoids, lignans, nucleosides, amino acids, and steroids. Previous pharmacological researches indicated that I. indigotica possesses promising antivirus, antibacterial, immunoregulatory, anti-inflammation, and cholagogic effects. Importantly, it can inhibit various viruses, such as influenza, hepatitis B, mumps, herpes simplex, cytomegalovirus, and coxsachievirus. Clinically, it is frequently used to treat various viral diseases like viral influenza, parotitis and viral hepatitis. Consequently, I. indigotica may be beneficial for the prevention and treatment of coronavirus disease 2019 (COVID-19). SUMMARY: This paper reviewed the chemical constituents, pharmacological effects and clinical applications of I. indigotica which may guide further research and application of this plant.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.