Evidence map›Paper›PMID 33779544›Full record

ArticleeLife2021

An atlas of the binding specificities of transcription factors in

Tingting Wang, Wenju Sun, Ligang Fan, Canfeng Hua, Nan Wu, Shaorong Fan, Jilin Zhang, Xin Deng, Jian Yan

Open access · goldAbstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
  2. ThemBio · 2026
    Article
  3. An allantoin-inducible glyoxylate utilization pathway inMicrobiology (Reading, England) · 2025
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  6. aBIOTECH · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Exploring aggregation genes in aJournal of bacteriology · 2025
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Harnessing regulatory networks in Actinobacteria for natural product discovery.Journal of industrial microbiology & biotechnology · 2024
    Review
  18. Article
  19. Spatial heterogeneity in biofilm metabolism elicited by local control of phenazine methylation.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Tingting Wang *Department of Biomedical Sciences, City University of Hong Kong, Kowloon Tong, Hong Kong SAR, China.
Wenju Sun *School of Medicine, Northwest University, Xi'an, China.
Ligang Fan *Department of Biomedical Sciences, City University of Hong Kong, Kowloon Tong, Hong Kong SAR, China.
Canfeng Hua *Department of Biomedical Sciences, City University of Hong Kong, Kowloon Tong, Hong Kong SAR, China.
Nan WuSchool of Medicine, Northwest University, Xi'an, China.
Shaorong FanSchool of Medicine, Northwest University, Xi'an, China.
Jilin ZhangDepartment of Medical Biochemistry and Biophysics, Karolinska Institutet, Solna, Sweden.
Xin DengDepartment of Biomedical Sciences, City University of Hong Kong, Kowloon Tong, Hong Kong SAR, China.
Jian YanDepartment of Biomedical Sciences, City University of Hong Kong, Kowloon Tong, Hong Kong SAR, China.ORCID 0000-0002-1267-2870
City University of Hong Kong · HKNorthwest University · CNKarolinska Institutet · SE

Funding

China Postdoctoral Science Foundation 2019M663794China Postdoctoral Science Foundation 2019M663799City University of Hong Kong 7005314City University of Hong Kong 9610424City University of Hong Kong 9667188National Natural Science Foundation of China 31870116National Natural Science Foundation of China 31900443National Natural Science Foundation of China 32070596National Natural Science Foundation of China 8187364Research Grants Council, University Grants Committee 11101619Research Grants Council, University Grants Committee 21100420Research Grants Council, University Grants Committee 21103018
6 · The paper itself

Abstract

A high-throughput systematic evolution of ligands by exponential enrichment assay was applied to 371 putative TFs in

Indexed as

Gene Expression Regulation, BacterialBacterial ProteinsBase SequencePseudomonas aeruginosaSequence AlignmentTranscription FactorsVirulenceVirulence FactorsBacterial ProteinsTranscription FactorsVirulence Factorsdna binding specificitygene expressiongeneticsgenomicsinfectious diseasemicrobiologyPseudomonas aeruginosatranscriptional regulation networktranscription factorsvirulence

Identifiers

PMID33779544
PMCPMC8041468
OpenAlexW3152123108

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.