Evidence map›Paper›PMID 33779310›Full record

ArticleThyroid : official journal of the American Thyroid Association2021

The Iodide Transport Defect-Causing Y348D Mutation in the Na

Andrea Reyna-Neyra, Lara Jung, Mayukh Chakrabarti, Mikel X Suárez, L Mario Amzel, Nancy Carrasco

Open access · greenAbstract read
In one paragraph

Article in Thyroid : official journal of the American Thyroid Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
5.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Lipid-Peptide-mRNA Nanoparticles Augment Radioiodine Uptake in Anaplastic Thyroid Cancer.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Article
  9. Brief Report: A Novel Sodium/Iodide Symporter Mutation, S356F, Causing Congenital Hypothyroidism.Thyroid : official journal of the American Thyroid Association · 2022
    Article
  10. Silent but Not Harmless: A SynonymousFrontiers in endocrinology · 2022
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Andrea Reyna-NeyraDepartment of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Lara JungDepartment of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Mayukh ChakrabartiDepartment of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Mikel X SuárezDepartment of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
L Mario AmzelDepartment of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Nancy CarrascoDepartment of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.ORCID 0000-0001-8586-6249
Vanderbilt University · USJohns Hopkins University · US

Funding

Mechanism of I- transport by the Na+/l- symporter (NIS)R01GM114250 · NIGMS · YALE UNIVERSITY · PI Nancy Carrasco · 2016 to 2026
$4.8M
NIGMS NIH HHS R01 GM114250
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Amino Acid SubstitutionBiological TransportBiotinylationCell MembraneCongenital HypothyroidismDNAGlycosylationHumansHydrophobic and Hydrophilic InteractionsIodineIodine RadioisotopesMutagenesis, Site-DirectedMutationSodium-Iodide SymportersSubcellular FractionsSymportersDNAIodineIodine RadioisotopesSodium-Iodide SymportersSymportersintracellular retention of NISiodide transport defect-causing NIS mutationsmolecular dynamics simulationssodium/iodide symporterY348D NIS

Identifiers

PMID33779310
PMCPMC8377515
OpenAlexW3144864400

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.