Evidence map›Paper›PMID 33779244›Full record

SynthesisJournal of the American Heart Association2021

Do Women Require Less Permanent Pacemaker After Transcatheter Aortic Valve Implantation? A Meta-Analysis and Meta-Regression.

Justine M Ravaux, Michele Di Mauro, Kevin Vernooy, Arnoud W Van't Hof, Leo Veenstra, Suzanne Kats, Jos G Maessen, Roberto Lorusso

Open access · goldAbstract readMeta-AnalysisReview
In one paragraph

Synthesis in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Pacemaker Status and 5-Year Mortality After TAVI: A Sex-Specific Analysis.European journal of clinical investigation · 2026
    Article
  3. How Sex and Race/Ethnicity Influence Interventional Cardiology Outcomes: What Do We Know?Journal of the Society for Cardiovascular Angiography & Interventions · 2026
    Review
  4. The Effect of Sacubitril/Valsartan on Supraventricular and Ventricular Arrhythmias in Patients With Heart Failure.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2025
    Article
  5. Aortic Stenosis: Time for a Sex-Based Approach?Journal of clinical medicine · 2025
    Review
  6. Observational
  7. Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Justine M RavauxDepartment of Cardio-Thoracic Surgery Heart and Vascular Centre Maastricht University Medical Centre (MUMC) Maastricht The Netherlands.
Michele Di MauroDepartment of Cardio-Thoracic Surgery Heart and Vascular Centre Maastricht University Medical Centre (MUMC) Maastricht The Netherlands.
Kevin VernooyCardiovascular Research Institute Maastricht (CARIM)Maastricht University Medical Center Maastricht The Netherlands.
Arnoud W Van't HofCardiovascular Research Institute Maastricht (CARIM)Maastricht University Medical Center Maastricht The Netherlands.
Leo VeenstraCardiovascular Research Institute Maastricht (CARIM)Maastricht University Medical Center Maastricht The Netherlands.
Suzanne KatsDepartment of Cardio-Thoracic Surgery Heart and Vascular Centre Maastricht University Medical Centre (MUMC) Maastricht The Netherlands.
Jos G MaessenDepartment of Cardio-Thoracic Surgery Heart and Vascular Centre Maastricht University Medical Centre (MUMC) Maastricht The Netherlands.
Roberto LorussoDepartment of Cardio-Thoracic Surgery Heart and Vascular Centre Maastricht University Medical Centre (MUMC) Maastricht The Netherlands.
Maastricht University Medical Centre · NLMaastricht University · NLRadboud University Nijmegen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Limited clinical evidence and literature are available about the potential impact of sex on permanent pacemaker implantation (PPI) after transcatheter aortic valve implantation (TAVI). The aim of this work was to evaluate the relationship between sexes and atrioventricular conduction disturbances requiring PPI after TAVI. Methods and Results Data were obtained from 46 studies from PubMed reporting information about the impact of patient sex on PPI after TAVI. Total proportions with 95% Cls were reported. Funnel plot and Egger test were used for estimation of publication bias. The primary end point was 30-day or in-hospital PPI after TAVI, with odds ratios and 95% CIs extracted. A total of 70 313 patients were included, with a cumulative proportion of 51.5% of women (35 691 patients; 95% CI, 50.2-52.7). The proportion of women undergoing TAVI dropped significantly over time (

Indexed as

ElectrocardiographyAortic Valve StenosisAtrioventricular BlockFemaleHumansMalePacemaker, ArtificialRisk FactorsSex FactorsTranscatheter Aortic Valve Replacementpermanent pacemakersextranscatheter aortic valve implantationwomen

Identifiers

PMID33779244
PMCPMC8174375
OpenAlexW3149067851

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.