Evidence map›Paper›PMID 33778967›Full record

ArticleAnimal genetics2021

Genome-wide association study of fleece traits in Inner Mongolia Cashmere goats.

F H Wang, L Zhang, G Gong, X C Yan, L T Zhang, F T Zhang, H F Liu, Q Lv, Z Y Wang, R J Wang and 7 more

Open access · hybridAbstract read
In one paragraph

Article in Animal genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
6.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Review
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  10. Review
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  12. Deciphering the molecular drivers for cashmere/pashmina fiber production in goats: a comprehensive review.Mammalian genome : official journal of the International Mammalian Genome Society · 2025
    Review
  13. Article
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  16. Article
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  18. Article
  19. Molecular insights into Pashmina fiber production: comparative skin transcriptomic analysis of Changthangi goats and sheep.Mammalian genome : official journal of the International Mammalian Genome Society · 2024
    Article
  20. Genetic characterization of cashmere goat (Frontiers in genetics · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 2 institutions in 1 country.

F H WangCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot, Inner Mongolia, 010018, China.ORCID https://orcid.org/0000-0001-7187-4424
L ZhangCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot, Inner Mongolia, 010018, China.
G GongCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot, Inner Mongolia, 010018, China.
X C YanCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot, Inner Mongolia, 010018, China.
L T ZhangCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot, Inner Mongolia, 010018, China.
F T ZhangCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot, Inner Mongolia, 010018, China.
H F LiuCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot, Inner Mongolia, 010018, China.
Q LvCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot, Inner Mongolia, 010018, China.
Z Y WangCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot, Inner Mongolia, 010018, China.
R J WangCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot, Inner Mongolia, 010018, China.
Y J ZhangCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot, Inner Mongolia, 010018, China.
Z X WangCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot, Inner Mongolia, 010018, China.
Z H LiuCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot, Inner Mongolia, 010018, China.
L B HeKey Laboratory of Mutton Sheep Genetics and Breeding, Ministry of Agriculture and Rural Affairs, Hohhot, 010018, China.
R SuCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot, Inner Mongolia, 010018, China.ORCID https://orcid.org/0000-0001-8386-7408
Y H ZhaoCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot, Inner Mongolia, 010018, China.
J Q LiCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot, Inner Mongolia, 010018, China.ORCID https://orcid.org/0000-0001-9159-5916
Inner Mongolia Agricultural University · CNMinistry of Agriculture and Rural Affairs · CN

Funding

Central Government Guiding Special Funds for Development of Local Science and Technology 2020ZY0007China Agriculture Research System CARS-39-06National Natural Science Foundation of China 31860637Research and Innovation Projects for Postgraduates B20191136ZScience and Technology Project of Inner Mongolia Autonomous Region 2019GG243Youth Foundation in Inner Mongolia Agricultural University QN202003
6 · The paper itself

Abstract

Inner Mongolia Cashmere goat is a well-known local cashmere goat breed in China. It is famous for excellent fleece quality and a significant advantage in cashmere yield compared to other cashmere goat breeds. In this study, a genome-wide association study was used to investigate fiber length, fiber diameter, and cashmere yield of 192 Inner Mongolia Cashmere goats using the Illumina GoatSNP52K Beadchip panel. We discovered that four single nucleotide polymorphisms (SNPs) reached genome-wide significance levels. These SNPs were located in some genes, e.g. FGF12, SEMA3D, EVPL, and SOX5, possibly related to fleece traits in Inner Mongolia Cashmere goat. Gene ontology enrichment analysis revealed that these genes were enriched in several biological pathways that were involved in hair follicle development in cashmere goats. In summary, the identified significant SNPs and genes provide useful information to explore genetic mechanisms underlying the variation in fleece traits and genomic selection of Chinese cashmere goat.

Indexed as

HairAnimalsChinaGene OntologyGenome-Wide Association StudyGoatsPolymorphism, Single Nucleotidefleece traitsgenome-wide association studyGoatSNP52K BeadchipInner Mongolia Cashmere goats

Identifiers

PMID33778967
PMCPMC8251931
OpenAlexW3145332685

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.