Evidence map›Paper›PMID 33778886›Full record

ArticleEuropean heart journal2021

C-reactive protein predicts outcome in COVID-19: is it also a therapeutic target?

Mark B Pepys

Registry-linked trialAbstract readEditorialComment
In one paragraph

Article in European heart journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04898062 (Randomized, Controlled, Proof-Of-Concept Trial of CRP-Apheresis for Attenuation of Pulmonary MYocardial and/or Kidney Injury in COvid-19), which is not on this map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04898062 nawithdrawnnot on this map

Randomized, Controlled, Proof-Of-Concept Trial of CRP-Apheresis for Attenuation of Pulmonary MYocardial and/or Kidney Injury in COvid-19

TypeinterventionalSponsorPentracor GmbHRan2021 to 2023Enrolled0ConditionsCovid19ArmsCRP-apheresis
3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Investigation of Serum Endocan Levels in SARS-CoV-2 Patients.International journal of molecular sciences · 2024
    Article
  3. Review
  4. Editorial: Biology of C-reactive protein.Frontiers in immunology · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Mark B PepysWolfson Drug Discovery Unit, UCL Royal Free Campus, London, UK.ORCID 0000-0003-2614-3248

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

COVID-19C-Reactive ProteinHumansSARS-CoV-2C-Reactive Protein

Identifiers

PMID33778886
PMCPMC8083631

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.