Evidence map›Paper›PMID 33778816›Full record

ArticleInternational journal of biopharmaceutical sciences2020

The Role of the Microbiome in Cancer and the Development of Cancer Therapeutics.

Kaitlyn C Belknap, Andrea L Cote, Colin M McGill, Cheryl P Andam, Brian M Barth

Open access · greenAbstract read
In one paragraph

Article in International journal of biopharmaceutical sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 86% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Kaitlyn C BelknapDepartment of Molecular, Cellular and Biomedical Sciences, University of New Hampshire, Durham NH 03824 USA.
Andrea L CoteDepartment of Molecular, Cellular and Biomedical Sciences, University of New Hampshire, Durham NH 03824 USA.
Colin M McGillDepartment of Chemistry, University of Alaska Anchorage, Anchorage AK 99508 USA.
Cheryl P AndamDepartment of Molecular, Cellular and Biomedical Sciences, University of New Hampshire, Durham NH 03824 USA.ORCID 0000-0003-4428-0924
Brian M BarthDepartment of Molecular, Cellular and Biomedical Sciences, University of New Hampshire, Durham NH 03824 USA.ORCID 0000-0002-3542-1804
Albany State University · USUniversity of Alaska Anchorage · US

Funding

Regulation of Ceramide-Based Therapeutics in Acute Myeloid LeukemiaK22CA190674 · NCI · UNIVERSITY OF NEW HAMPSHIRE · PI BARTH, BRIAN MICHAEL · 2016 to 2018
$485k
NCI NIH HHS K22 CA190674
6 · The paper itself

Abstract

Cancer is caused by a compilation of hereditary and environmental factors. In the past decade, next-generation sequencing has revealed the extent to which the microbiome influences the maintenance of homeostasis and therefore the prevention of diseases such as cancer. Current research efforts explore the interaction between cancer and the microbiome, and the results are anticipated to transform how clinicians approach cancer treatment. There is a plausible transition from the use of human genetic biomarkers to microbiomic biomarkers for genomic diagnostics. Considering the expanding knowledge of the ways in which the microbiome can affect the development of cancer, clinicians treating cancer patients should be considerate of how the microbiome can influence the host-drug or microbiome-cancer interactions. Recognition of the importance of the microbiome within the field of oncology is pertinent to understanding and furthering cancer development and treatment.

Indexed as

breast cancercancer therapeuticscolorectal cancergastric cancerleukemiamicrobiomeskin cancer

Identifiers

PMID33778816
PMCPMC7993822
OpenAlexW3142929703

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.