Evidence map›Paper›PMID 33778749›Full record

ArticleRadiology. Imaging cancer2020

Richard A Komoroski, Jing-Huei Lee, Jeffrey A Welge, Jonathan A Dudley, Wen-Jang Chu, Mary C Mahoney

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Radiology. Imaging cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 81% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Richard A KomoroskiDepartment of Psychiatry and Behavioral Neuroscience (R.A.K., J.H.L., J.A.W., W.J.C.) and Department of Radiology (M.C.M.), College of Medicine, University of Cincinnati, 234 Goodman St, ML 761, Cincinnati, OH 45267; Department of Biomedical Engineering, College of Engineering and Applied Science, University of Cincinnati, Cincinnati, Ohio (J.H.L.); and Department of Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio (J.A.D.).
Jing-Huei LeeDepartment of Psychiatry and Behavioral Neuroscience (R.A.K., J.H.L., J.A.W., W.J.C.) and Department of Radiology (M.C.M.), College of Medicine, University of Cincinnati, 234 Goodman St, ML 761, Cincinnati, OH 45267; Department of Biomedical Engineering, College of Engineering and Applied Science, University of Cincinnati, Cincinnati, Ohio (J.H.L.); and Department of Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio (J.A.D.).
Jeffrey A WelgeDepartment of Psychiatry and Behavioral Neuroscience (R.A.K., J.H.L., J.A.W., W.J.C.) and Department of Radiology (M.C.M.), College of Medicine, University of Cincinnati, 234 Goodman St, ML 761, Cincinnati, OH 45267; Department of Biomedical Engineering, College of Engineering and Applied Science, University of Cincinnati, Cincinnati, Ohio (J.H.L.); and Department of Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio (J.A.D.).
Jonathan A DudleyDepartment of Psychiatry and Behavioral Neuroscience (R.A.K., J.H.L., J.A.W., W.J.C.) and Department of Radiology (M.C.M.), College of Medicine, University of Cincinnati, 234 Goodman St, ML 761, Cincinnati, OH 45267; Department of Biomedical Engineering, College of Engineering and Applied Science, University of Cincinnati, Cincinnati, Ohio (J.H.L.); and Department of Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio (J.A.D.).
Wen-Jang ChuDepartment of Psychiatry and Behavioral Neuroscience (R.A.K., J.H.L., J.A.W., W.J.C.) and Department of Radiology (M.C.M.), College of Medicine, University of Cincinnati, 234 Goodman St, ML 761, Cincinnati, OH 45267; Department of Biomedical Engineering, College of Engineering and Applied Science, University of Cincinnati, Cincinnati, Ohio (J.H.L.); and Department of Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio (J.A.D.).
Mary C MahoneyDepartment of Psychiatry and Behavioral Neuroscience (R.A.K., J.H.L., J.A.W., W.J.C.) and Department of Radiology (M.C.M.), College of Medicine, University of Cincinnati, 234 Goodman St, ML 761, Cincinnati, OH 45267; Department of Biomedical Engineering, College of Engineering and Applied Science, University of Cincinnati, Cincinnati, Ohio (J.H.L.); and Department of Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio (J.A.D.).ORCID 0000-0001-6139-9201
University of Cincinnati Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To determine whether MR spectroscopic assessment of fine-needle aspiration (FNA) biopsy specimens from suspicious breast lesions could be used to improve the diagnostic utility of FNA biopsies for the characterization of breast lesions. Materials and Methods: In this prospective study, a previously reported technique using high-spatial-resolution proton MR spectroscopy was modified and used to examine the utility of FNA biopsies in the evaluation of suspicious breast lesions. Tissue samples from 115 lesions (from 102 women; average age, 54 years) were excised by using FNA and core biopsies and were collected between September 7, 2012, and April 11, 2014. Histologic results from core biopsy specimens determined the lesions to be benign ( Results: Of the 115 samples, 69 (60%) yielded no usable MR spectra. Analysis of the 46 with usable spectra found that only the difference in PC/tCr between benign and cancer lesions was statistically significant ( Conclusion: Given that 60% of FNA biopsy specimens yielded no usable spectra and that results were largely inconclusive when derived from usable spectra, the combined MR and FNA technique, as modified and implemented in this study, is of little value for detection and diagnosis of breast cancer.

Indexed as

Breast NeoplasmsMagnetic Resonance SpectroscopyBiopsy, Fine-NeedleBreastFemaleHumansMiddle AgedProspective Studies

Identifiers

PMID33778749
PMCPMC7983769
OpenAlexW3106979993

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.