ReviewRadiology. Cardiothoracic imaging2021
Chronic Lung Allograft Dysfunction: Review of CT and Pathologic Findings.
Review in Radiology. Cardiothoracic imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed.
- Early post-transplant ventilation and perfusion assessment using phase-resolved functional lung MRI.La Radiologia medica · 2026Article
- Mesothelial Plasticity Specifies Divergent Pleural Immune Circuits that Instruct Lung Regeneration versus Degeneration.Research square · 2026Article
- A Tale of Two Lungs: 99m Tc-MAA Pulmonary Scintigraphy Reveals Unilateral Chronic Lung Allograft Dysfunction (CLAD) After Bilateral Living-Donor Lobar Lung Transplants (LDLLT).Clinical nuclear medicine · 2026Article
- Article
- A Potential Novel Molecular Interaction in Bronchiolitis Obliterans Syndrome in Lung Transplantation Patients: The Role of SERPINA3 and Osteoprotegerin.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026Article
- Tolerability and Effectiveness of Glucagon-Like Peptide-1 Receptor Agonists in Lung Transplant Recipients: A Single Center Report.Transplantation proceedings · 2025Article
- Review
- HyperpolarizedJHLT open · 2024Article
- Article
- Long-term outcomes of lung transplantation withFrontiers in transplantation · 2024Article
- Graft-versus-host disease may cause pulmonary restriction, but not all restriction is graft-versus-host disease.Blood advances · 2022Article
- Transition from BOS to RAS impairs prognosis after lung transplantation-CLAD subtype analysis by CT volumetry.PloS one · 2022Article
- Lung Transplantation: CT Assessment of Chronic Lung Allograft Dysfunction (CLAD).Diagnostics (Basel, Switzerland) · 2021Review
- Complications of lung transplantation on computed tomography: pictorial essay.Radiologia brasileiraArticle
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic lung allograft dysfunction (CLAD) is the most common cause of mortality in lung transplant recipients after the 1st year of transplantation. CLAD has traditionally been classified into two distinct obstructive and restrictive forms: bronchiolitis obliterans syndrome and restrictive allograft syndrome. However, CLAD may manifest with a spectrum of imaging and pathologic findings and a combination of obstructive and restrictive physiologic abnormalities. Although the initial CT manifestations of CLAD may be nonspecific, the progression of findings at follow-up should signal the possibility of CLAD and may be present on imaging studies prior to the development of functional abnormalities of the lung allograft. This review encompasses the evolution of CT findings in CLAD, with emphasis on the underlying pathogenesis and pathologic condition, to enhance understanding of imaging findings. The purpose of this article is to familiarize the radiologist with the initial and follow-up CT findings of the obstructive, restrictive, and mixed forms of CLAD, for which early diagnosis and treatment may result in improved survival.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.