Evidence map›Paper›PMID 33778595›Full record

ArticleRadiology. Cardiothoracic imaging2020

Utility of FDG PET and Cardiac MRI in Diagnosis and Monitoring of Immunosuppressive Treatment in Cardiac Sarcoidosis.

Richard A Coulden, Emer P Sonnex, Jonathan T Abele, Andrew M Crean

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Radiology. Cardiothoracic imaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 38 citations in OpenAlex.

  1. World journal of nuclear medicine · 2026
    Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
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  11. Prednisone vs methotrexate in treatment naïve cardiac sarcoidosis.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Article
  12. [Hybrid PET/MRI for inflammatory cardiomyopathy].Radiologie (Heidelberg, Germany) · 2022
    Review
  13. Article
  14. Article
  15. Epidemiology, Pathogenesis, and Diagnosis of Cardiac Sarcoidosis.Methodist DeBakey cardiovascular journal · 2022
    Review
  16. State-of-the-Art Treatments for Sarcoidosis.Methodist DeBakey cardiovascular journal · 2022
    Review
  17. Article
  18. Article
  19. Article
  20. Utility ofIndian heart journal
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Richard A CouldenDepartment of Radiology and Diagnostic Imaging, University of Alberta Hospital, 8440 112 St NW, Edmonton, AB, Canada T6G 2B7 (R.A.C., E.P.S., J.T.A.); and Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada (A.M.C.).ORCID https://orcid.org/0000-0002-6920-8833
Emer P SonnexDepartment of Radiology and Diagnostic Imaging, University of Alberta Hospital, 8440 112 St NW, Edmonton, AB, Canada T6G 2B7 (R.A.C., E.P.S., J.T.A.); and Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada (A.M.C.).ORCID https://orcid.org/0000-0003-4774-611X
Jonathan T AbeleDepartment of Radiology and Diagnostic Imaging, University of Alberta Hospital, 8440 112 St NW, Edmonton, AB, Canada T6G 2B7 (R.A.C., E.P.S., J.T.A.); and Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada (A.M.C.).ORCID https://orcid.org/0000-0002-5311-1332
Andrew M CreanDepartment of Radiology and Diagnostic Imaging, University of Alberta Hospital, 8440 112 St NW, Edmonton, AB, Canada T6G 2B7 (R.A.C., E.P.S., J.T.A.); and Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada (A.M.C.).
University of Alberta Hospital · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare the contributions of cardiac MRI and PET in the diagnosis and management of cardiac sarcoidosis (CS), with particular reference to quantitative measures. MATERIALS AND

methodsThis is a retrospective, observational study of 31 patients (mean age, 45.7 years) with proven extracardiac sarcoidosis and possible CS who were investigated with fluorine 18 fluorodeoxyglucose (FDG) PET/CT and cardiac MRI. Patients were treated at physicians' discretion with repeat combined imaging after an interval of 102-770 days (median, 228 days).

resultsSignificant myocardial FDG uptake was shown on visit 1 (myocardial maximum standardized uptake value [SUV

conclusionMyocardial FDG uptake in patients suspected of having CS is presumed to represent active inflammation. When treated with corticosteroids, this resolved or regressed at follow-up, with an improvement in LVEF and FDG-avid thoracic disease. Patients who were untreated showed no change in any parameter. Quantification of FDG-avid myocardium using cardiac metabolic volume is proposed as a useful objective measure for assessing response to therapy.© RSNA, 2020See also commentary by Gutberlet in this issue.

Identifiers

PMID33778595
PMCPMC7977729
OpenAlexW3080736782

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.