Evidence map›Paper›PMID 33778567›Full record

ArticleRadiology. Cardiothoracic imaging2020

Differences in Clinical and Imaging Presentation of Pediatric Patients with COVID-19 in Comparison with Adults.

Amei Chen, Jun-Xiang Huang, Yuting Liao, Zaosong Liu, Dandan Chen, Chongzhe Yang, Rui-Meng Yang, Xinhua Wei

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Radiology. Cardiothoracic imaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 6 pooled it
2.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 6 syntheses or guidelines pooled it, 121 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. [Pneumonia in childhood and adolescence].Radiologie (Heidelberg, Germany) · 2025
    Review
  8. SARS-CoV-2 paediatric chest X-ray findings during the Omicron variant wave.Southern African journal of infectious diseases · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Observational
  14. Article
  15. Article
  16. Review
  17. Article
  18. COVID-19 in Children.Pediatric clinics of North America · 2022
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Amei ChenDepartment of Radiology, Guangzhou First Hospital, The Second Affiliated Hospital, South China University of Technology, No. 1 Panfu Road, Guangzhou 510180, China (A.C., Z.L., D.C., R.Y., X.W.); Department of Anesthesiology, Guangzhou Women and Children's Medical Center, Guangzhou, Guangdong, China (J.H.); GE Healthcare, Guangzhou, China (Y.L.); and Department of Geriatrics, Guangzhou First People's Hospital, The Second Affiliated Hospital, South China University of Technology, Guangzhou, China (C.Y.).ORCID 0000-0002-2074-6470
Jun-Xiang HuangDepartment of Radiology, Guangzhou First Hospital, The Second Affiliated Hospital, South China University of Technology, No. 1 Panfu Road, Guangzhou 510180, China (A.C., Z.L., D.C., R.Y., X.W.); Department of Anesthesiology, Guangzhou Women and Children's Medical Center, Guangzhou, Guangdong, China (J.H.); GE Healthcare, Guangzhou, China (Y.L.); and Department of Geriatrics, Guangzhou First People's Hospital, The Second Affiliated Hospital, South China University of Technology, Guangzhou, China (C.Y.).ORCID 0000-0002-9743-0466
Yuting LiaoDepartment of Radiology, Guangzhou First Hospital, The Second Affiliated Hospital, South China University of Technology, No. 1 Panfu Road, Guangzhou 510180, China (A.C., Z.L., D.C., R.Y., X.W.); Department of Anesthesiology, Guangzhou Women and Children's Medical Center, Guangzhou, Guangdong, China (J.H.); GE Healthcare, Guangzhou, China (Y.L.); and Department of Geriatrics, Guangzhou First People's Hospital, The Second Affiliated Hospital, South China University of Technology, Guangzhou, China (C.Y.).ORCID 0000-0002-7186-1962
Zaosong LiuDepartment of Radiology, Guangzhou First Hospital, The Second Affiliated Hospital, South China University of Technology, No. 1 Panfu Road, Guangzhou 510180, China (A.C., Z.L., D.C., R.Y., X.W.); Department of Anesthesiology, Guangzhou Women and Children's Medical Center, Guangzhou, Guangdong, China (J.H.); GE Healthcare, Guangzhou, China (Y.L.); and Department of Geriatrics, Guangzhou First People's Hospital, The Second Affiliated Hospital, South China University of Technology, Guangzhou, China (C.Y.).ORCID 0000-0002-1483-2807
Dandan ChenDepartment of Radiology, Guangzhou First Hospital, The Second Affiliated Hospital, South China University of Technology, No. 1 Panfu Road, Guangzhou 510180, China (A.C., Z.L., D.C., R.Y., X.W.); Department of Anesthesiology, Guangzhou Women and Children's Medical Center, Guangzhou, Guangdong, China (J.H.); GE Healthcare, Guangzhou, China (Y.L.); and Department of Geriatrics, Guangzhou First People's Hospital, The Second Affiliated Hospital, South China University of Technology, Guangzhou, China (C.Y.).
Chongzhe YangDepartment of Radiology, Guangzhou First Hospital, The Second Affiliated Hospital, South China University of Technology, No. 1 Panfu Road, Guangzhou 510180, China (A.C., Z.L., D.C., R.Y., X.W.); Department of Anesthesiology, Guangzhou Women and Children's Medical Center, Guangzhou, Guangdong, China (J.H.); GE Healthcare, Guangzhou, China (Y.L.); and Department of Geriatrics, Guangzhou First People's Hospital, The Second Affiliated Hospital, South China University of Technology, Guangzhou, China (C.Y.).ORCID 0000-0002-0338-8245
Rui-Meng YangDepartment of Radiology, Guangzhou First Hospital, The Second Affiliated Hospital, South China University of Technology, No. 1 Panfu Road, Guangzhou 510180, China (A.C., Z.L., D.C., R.Y., X.W.); Department of Anesthesiology, Guangzhou Women and Children's Medical Center, Guangzhou, Guangdong, China (J.H.); GE Healthcare, Guangzhou, China (Y.L.); and Department of Geriatrics, Guangzhou First People's Hospital, The Second Affiliated Hospital, South China University of Technology, Guangzhou, China (C.Y.).ORCID 0000-0003-2768-9429
Xinhua WeiDepartment of Radiology, Guangzhou First Hospital, The Second Affiliated Hospital, South China University of Technology, No. 1 Panfu Road, Guangzhou 510180, China (A.C., Z.L., D.C., R.Y., X.W.); Department of Anesthesiology, Guangzhou Women and Children's Medical Center, Guangzhou, Guangdong, China (J.H.); GE Healthcare, Guangzhou, China (Y.L.); and Department of Geriatrics, Guangzhou First People's Hospital, The Second Affiliated Hospital, South China University of Technology, Guangzhou, China (C.Y.).ORCID 0000-0002-6801-4826
Second Affiliated Hospital of Guangzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo characterize and compare the initial clinical and imaging features of coronavirus disease 2019 (COVID-19) in pediatric and adult patients undergoing chest CT. MATERIALS AND

methodsA total of 61 patients, consisting of 47 adults (aged 18 years or older) and 14 pediatric patients (aged younger than 18 years) with laboratory-confirmed COVID-19 confirmed by real-time reverse-transcription polymerase chain reaction between January 25 and February 15, 2020, were enrolled in this study. All patients underwent chest CT within 3 days after the initial reverse transcription polymerase chain reaction test. The clinical presentation, serum markers, and CT findings were assessed and compared between the adult and pediatric patients.

resultsFever was less common in pediatric patients than in adults (six of 14, 42.9% vs 39 of 47, 83%;

conclusionCompared with adults, pediatric patients with COVID-19 showed distinctive clinical and CT features. Pediatric patients tend to have milder clinical symptoms, fewer positive results at CT, and less extensive involvement at imaging. Bronchial wall thickening was relatively more frequent on CT images from pediatric patients with COVID-19 in comparison with adults.

Identifiers

PMID33778567
PMCPMC7233434
OpenAlexW3014483829

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.