Evidence map›Paper›PMID 33778521›Full record

ArticleRadiology. Cardiothoracic imaging2019

Myocardial Stress Perfusion MRI Using Regadenoson: A Weight-based Approach in Infants and Young Children.

James C Wilkinson, Tam T Doan, Robert W Loar, Amol S Pednekar, Premal M Trivedi, Prakash M Masand, Cory V Noel

Open access · bronzeAbstract read
In one paragraph

Article in Radiology. Cardiothoracic imaging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Society for cardiovascular magnetic resonance expert consensus statement on quantitative myocardial perfusion cardiovascular magnetic resonance imaging.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
    Guideline
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

James C WilkinsonDepartment of Pediatrics, Division of Pediatric Cardiology (J.C.W., T.T.D., R.W.L., C.V.N.), Department of Radiology (A.S.P., P.M.M.), and Department of Pediatric Anesthesiology (P.M.T.), Texas Children's Hospital, Baylor College of Medicine, 6651 Main St, Legacy Tower, E1920, Houston, TX 77030.ORCID 0000-0003-2838-7465
Tam T DoanDepartment of Pediatrics, Division of Pediatric Cardiology (J.C.W., T.T.D., R.W.L., C.V.N.), Department of Radiology (A.S.P., P.M.M.), and Department of Pediatric Anesthesiology (P.M.T.), Texas Children's Hospital, Baylor College of Medicine, 6651 Main St, Legacy Tower, E1920, Houston, TX 77030.ORCID 0000-0002-8256-1535
Robert W LoarDepartment of Pediatrics, Division of Pediatric Cardiology (J.C.W., T.T.D., R.W.L., C.V.N.), Department of Radiology (A.S.P., P.M.M.), and Department of Pediatric Anesthesiology (P.M.T.), Texas Children's Hospital, Baylor College of Medicine, 6651 Main St, Legacy Tower, E1920, Houston, TX 77030.
Amol S PednekarDepartment of Pediatrics, Division of Pediatric Cardiology (J.C.W., T.T.D., R.W.L., C.V.N.), Department of Radiology (A.S.P., P.M.M.), and Department of Pediatric Anesthesiology (P.M.T.), Texas Children's Hospital, Baylor College of Medicine, 6651 Main St, Legacy Tower, E1920, Houston, TX 77030.ORCID 0000-0002-5686-3417
Premal M TrivediDepartment of Pediatrics, Division of Pediatric Cardiology (J.C.W., T.T.D., R.W.L., C.V.N.), Department of Radiology (A.S.P., P.M.M.), and Department of Pediatric Anesthesiology (P.M.T.), Texas Children's Hospital, Baylor College of Medicine, 6651 Main St, Legacy Tower, E1920, Houston, TX 77030.
Prakash M MasandDepartment of Pediatrics, Division of Pediatric Cardiology (J.C.W., T.T.D., R.W.L., C.V.N.), Department of Radiology (A.S.P., P.M.M.), and Department of Pediatric Anesthesiology (P.M.T.), Texas Children's Hospital, Baylor College of Medicine, 6651 Main St, Legacy Tower, E1920, Houston, TX 77030.
Cory V NoelDepartment of Pediatrics, Division of Pediatric Cardiology (J.C.W., T.T.D., R.W.L., C.V.N.), Department of Radiology (A.S.P., P.M.M.), and Department of Pediatric Anesthesiology (P.M.T.), Texas Children's Hospital, Baylor College of Medicine, 6651 Main St, Legacy Tower, E1920, Houston, TX 77030.
Texas Children's Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo determine the safety and feasibility of stress cardiac MRI by using weight-based dosing of regadenoson in patients less than 40 kg and whether stress cardiac MRI affects patient management. MATERIALS AND

methodsAll patients less than 40 kg undergoing stress cardiac MRI by using weight-based dosing (8 μg/kg) of regadenoson were included in this retrospective single-center study. Hemodynamic response, adverse events, and cardiac MRI abnormalities in myocardial perfusion, wall motion, and delayed enhancement were evaluated. Patient management based on the results of the stress cardiac MRI were evaluated.

resultsForty-six consecutive stress cardiac MRI examinations were performed in 36 patients (median age, 9.0 years; age range, 2 months to 13.9 years) with congenital and acquired heart disease. Thirty-one of 46 (67.4%) studies were performed with the use of sedation. A myocardial perfusion defect was present in 20 of 46 (43.5%) studies, five with inducible defects only, and the remaining 15 with fixed or irreversible defects. In the 46 total studies, there were no major adverse events and nine (19.6%) minor adverse events including emesis (

conclusionWeight-based dosing of regadenoson for stress cardiac MRI was safe and feasible in infants and young children and played an integral role in the outcome and treatment decisions for children with coronary artery disease.© RSNA, 2019.

Identifiers

PMID33778521
PMCPMC7977799
OpenAlexW2989019936

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.