ArticleCJC open2021
Elevated Cardiac Troponin Levels in Geriatric Patients Without ACS: Role of Comorbidities.
Article in CJC open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
9 citing papers in PubMed, 17 citations in OpenAlex.
- Comparative prognostic value of high-sensitivity cardiac troponin T and NT-proBNP for 30-day mortality in non-cardiac critically ill patients.Scientific reports · 2026Article
- Troponin-T as predictor of mortality in patients attending the emergency department with atrial fibrillation.BMC cardiovascular disorders · 2024Article
- Comprehensive Quality Analysis of Conventional and Novel Biomarkers in Diagnosing and Predicting Prognosis of Coronary Artery Disease, Acute Coronary Syndrome, and Heart Failure, a Comprehensive Literature Review.Journal of cardiovascular translational research · 2024Review
- High sensitivity troponins and mortality in the population with metabolic dysfunction-associated steatotic liver disease.Scientific reports · 2024Article
- Management of Acute Coronary Syndromes in Older People: Comprehensive Review and Multidisciplinary Practice-Based Recommendations.Journal of clinical medicine · 2024Review
- Levels of high-sensitive troponin T and mid-regional pro-adrenomedullin after COVID-19 vaccination in vulnerable groups: monitoring cardiovascular safety of COVID-19 vaccination.Frontiers in cardiovascular medicine · 2024Article
- Admission high-sensitivity cardiac troponin levels as a prognostic indicator for in-hospital mortality rates in the elderly and very elderly COVID-19 patients.Archives of gerontology and geriatrics · 2023Article
- Comparative frequency and prognostic impact of myocardial injury in hospitalized patients with COVID-19 and Influenza.European heart journal open · 2021Article
- The impact of cardiac troponin in elderly patients in the absence of acute coronary syndrome: A systematic review.International journal of cardiology. Heart & vasculature · 2020Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundElevated levels of cardiac troponin T as measured by a high-sensitivity test (hscTnT) are common in geriatric patients with a large spectrum of comorbidities but without acute coronary syndrome (ACS). However, the relative contribution of individual comorbidities has never been clearly addressed. This study aimed to determine the relationship between hscTnT elevation as a response variable and individual comorbidities, and to estimate the impact of individual comorbidities on hscTnT elevation in geriatric patients free of ACS.
methodsA nonexperimental, retrospective, matched, longitudinal cohort study was designed to evaluate the files of 7062 geriatric patients (aged ≥ 65 years) without ACS. The hscTnT levels of the patients have already been measured in all evaluated medical records. The dataset was split into 2 groups (0 and 1) based on the individual comorbidity (0 and 1) and hscTnT levels (≤ 14 ng/L = 0 and > 14 ng/L = 1).
resultsOur results show that although age was positively and significantly correlated with hscTnT (r = 0.17,
conclusionsElevated hscTnT levels were mostly associated with renal insufficiency, cardiac myopathies, chronic obstructive pulmonary disease, diabetes, and anemia in geriatric patients without ACS. Developing guidelines to accurately evaluate hscTnT elevation in geriatric patients with comorbidities, without ACS, is clinically essential.
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Registered trials
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