Evidence map›Paper›PMID 33778410›Full record

ReviewJOR spine2021

Spine biomechanical testing methodologies: The controversy of consensus vs scientific evidence.

John J Costi, Eric H Ledet, Grace D O'Connell

Abstract readReview
In one paragraph

Review in JOR spine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed.

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  7. Intervertebral disc distraction stiffness predicts endplate subsidence following transforaminal interbody cage expansion: an ex vivo study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  8. Establishing a standardized biomechanical model for osteoporotic pincer (OF4) Fracture creation in human cadaveric spines: a novel experimental technique.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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  18. Impact of caudal segment bone fusion on rod load at the cranial segment in a two-level spinal interbody fusion construct- a biomechanical study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

John J CostiBiomechanics and Implants Research Group, Medical Device Research Institute, College of Science and Engineering Flinders University Adelaide Australia.ORCID https://orcid.org/0000-0002-8267-7837
Eric H LedetDepartment of Biomedical Engineering Rensselaer Polytechnic Institute Troy New York USA.
Grace D O'ConnellDepartment of Mechanical Engineering University of California-Berkeley Berkeley California USA.ORCID https://orcid.org/0000-0003-0746-1638

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biomechanical testing methodologies for the spine have developed over the past 50 years. During that time, there have been several paradigm shifts with respect to techniques. These techniques evolved by incorporating state-of-the-art engineering principles, in vivo measurements, anatomical structure-function relationships, and the scientific method. Multiple parametric studies have focused on the effects that the experimental technique has on outcomes. As a result, testing methodologies have evolved, but there are no standard testing protocols, which makes the comparison of findings between experiments difficult and conclusions about in vivo performance challenging. In 2019, the international spine research community was surveyed to determine the consensus on spine biomechanical testing and if the consensus opinion was consistent with the scientific evidence. More than 80 responses to the survey were received. The findings of this survey confirmed that while some methods have been commonly adopted, not all are consistent with the scientific evidence. This review summarizes the scientific literature, the current consensus, and the authors' recommendations on best practices based on the compendium of available evidence.

Indexed as

biomechanicsconsensuscontroversyin vitromechanical testingmethodologyspine

Identifiers

PMID33778410
PMCPMC7984003

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.