Evidence map›Paper›PMID 33778408›Full record

ArticleJOR spine2021

Single level posterolateral lumbar fusion in a New Zealand White rabbit (

James D Crowley, Rema A Oliver, Michael J Dan, Daniel J Wills, John W Rawlinson, Rebekah A Crasto, James M O'Connor, Gregory J Mitchell, Christopher J Tan, William R Walsh

Open access · goldAbstract read
In one paragraph

Article in JOR spine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

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  9. Lateral fenestration of lumbar intervertebral discs in rabbits: development and characterisation of an in vivo preclinical model with multi-modal endpoint analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

James D CrowleySurgical and Orthopaedic Research Laboratories, Prince of Wales Clinical School University of New South Wales Sydney, Prince of Wales Hospital Sydney New South Wales Australia.ORCID https://orcid.org/0000-0001-7884-4199
Rema A OliverSurgical and Orthopaedic Research Laboratories, Prince of Wales Clinical School University of New South Wales Sydney, Prince of Wales Hospital Sydney New South Wales Australia.
Michael J DanSurgical and Orthopaedic Research Laboratories, Prince of Wales Clinical School University of New South Wales Sydney, Prince of Wales Hospital Sydney New South Wales Australia.
Daniel J WillsSurgical and Orthopaedic Research Laboratories, Prince of Wales Clinical School University of New South Wales Sydney, Prince of Wales Hospital Sydney New South Wales Australia.
John W RawlinsonSurgical and Orthopaedic Research Laboratories, Prince of Wales Clinical School University of New South Wales Sydney, Prince of Wales Hospital Sydney New South Wales Australia.
Rebekah A CrastoSurgical and Orthopaedic Research Laboratories, Prince of Wales Clinical School University of New South Wales Sydney, Prince of Wales Hospital Sydney New South Wales Australia.
James M O'ConnorSurgical and Orthopaedic Research Laboratories, Prince of Wales Clinical School University of New South Wales Sydney, Prince of Wales Hospital Sydney New South Wales Australia.
Gregory J MitchellSurgical and Orthopaedic Research Laboratories, Prince of Wales Clinical School University of New South Wales Sydney, Prince of Wales Hospital Sydney New South Wales Australia.
Christopher J TanSurgical and Orthopaedic Research Laboratories, Prince of Wales Clinical School University of New South Wales Sydney, Prince of Wales Hospital Sydney New South Wales Australia.
William R WalshSurgical and Orthopaedic Research Laboratories, Prince of Wales Clinical School University of New South Wales Sydney, Prince of Wales Hospital Sydney New South Wales Australia.
UNSW Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe posterolateral lumbar fusion (PLF) New Zealand White (NZW) ( MATERIALS AND

methodsWe describe the surgical technique and perioperative patient care for single level PLF in a NZW rabbit model. Medical records from a single research facility were retrospectively reviewed for adult NZW rabbits that underwent single level PLF (L4-L5) between January 2016 and December 2019. The number of lumbar vertebrae per rabbit, fusion rates at 12 weeks using iliac crest autograft and complications are reported. Skeletal maturity was confirmed by preoperative fluoroscopic and radiographic documented closure of hindlimb physes.

resultsThe PLF rabbit surgical model and perioperative patient care is described. PLF was performed in 868 adult female entire NZW rabbits. The majority of rabbits had seven lumbar vertebrae (620/868; 71.4%), followed by six (221/868; 25.5%), and eight (27/868; 3.1%). Fusion rates at 12 weeks for PLF using iliac crest autograft as assessed by manual palpation and radiographic assessment was 76.9% and 70.0%, respectively. Postoperative complications included occasional partial autograft site wound dehiscence due to self-trauma.

conclusionsFor PLF rabbit models, a detailed understanding of the surgical technique, rabbit lumbar anatomy including number of lumbar vertebrae, and dietary and husbandry requirements of rabbits, is essential for execution of the model and animal welfare.

Indexed as

autograftbone graftfusionintertransverseposterolateralrabbitspinevertebrae

Identifiers

PMID33778408
PMCPMC7984023
OpenAlexW3115574183

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.