ArticleEnvironmental epidemiology (Philadelphia, Pa.)2020
Residential proximity to major roads and fecundability in a preconception cohort.
Article in Environmental epidemiology (Philadelphia, Pa.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Indoor and outdoor air pollution and couple fecundability: a systematic review.Human reproduction update · 2023Pooled it
- Dynamic Associations between Ambient PMEnvironment & health (Washington, D.C.) · 2026Article
- Racialized economic segregation in relation to fecundability in a preconception cohort study.Journal of urban health : bulletin of the New York Academy of Medicine · 2026Article
- Experiences of discrimination across the life course among pregnancy planners in the United States and Canada.SSM - population health · 2025Article
- Residential Exposure to PMPaediatric and perinatal epidemiology · 2025Article
- Impacts of Vehicle Emission Regulations and Local Congestion Policies on Birth Outcomes Associated with Traffic Air Pollution.Research report (Health Effects Institute) · 2025Article
- Exposure to residential greenness, perceived stress, and depressive symptoms in a North American preconception cohort.Environmental research · 2024Article
- Ambient air pollution and rate of spontaneous abortion.Environmental research · 2024Article
- Air pollution and fecundability in a North American preconception cohort study.Environment international · 2023Article
- Changes in Socioeconomic Disparities for Traffic-Related Air Pollution Exposure During Pregnancy Over a 20-Year Period in Texas.JAMA network open · 2023Article
- Association between traffic-related air pollution exposure and fertility-assisted births.Environmental research, health : ERH · 2023Article
- Associations between Residential Greenspace and Fecundability in a North American Preconception Cohort Study.Environmental health perspectives · 2023Article
- Maternal periconceptional environmental exposure and offspring with congenital heart disease: a case-control study in Guangzhou, China.BMC pregnancy and childbirth · 2023Article
- Using follicular fluid metabolomics to investigate the association between air pollution and oocyte quality.Environment international · 2022Article
- Association Between Neighborhood Disadvantage and Fertility Among Pregnancy Planners in the US.JAMA network open · 2022Article
- The effect of short term exposure to outdoor air pollution on fertility.Reproductive biology and endocrinology : RB&E · 2021Article
- Land use and semen quality: A fertility center cohort study.PloS one · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
Emerging evidence from animal and human studies indicates that exposure to traffic-related air pollution may adversely affect fertility.
methodsAmong 7,342 female pregnancy planners from the United States and 1,448 from Canada, we examined the association between residential proximity to major roads and fecundability, the per-cycle probability of conception. From 2013 to 2019, women 21-45 years old who were trying to conceive without fertility treatment completed an online baseline questionnaire and follow-up questionnaires every 8 weeks for up to 12 months or until pregnancy. We geocoded residential addresses reported at baseline and during follow-up, and calculated distance to nearest major roads and length of major roads within buffers of 50, 100, 300, and 400 meters around the residence as proxies for traffic-related air pollution. We used proportional probabilities regression models to estimate fecundability ratios (FRs) and 95% confidence intervals (CIs), adjusting for individual- and neighborhood-level characteristics.
resultsIn the United States, the FR comparing women who lived <50 meters with those who lived ≥400 meters from the closest major road was 0.88 (95% CI = 0.80, 0.98). The association among Canadian women was similar in magnitude, but less precise (FR = 0.93; 95% CI = 0.74, 1.16). Likewise, length of major roads within buffers of 50 and 100 meters was associated with lower fecundability in both countries; associations were attenuated within larger buffers.
conclusionsThese results are consistent with the hypothesis that traffic-related air pollution or other near-road exposures may adversely affect fecundability.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.