Evidence map›Paper›PMID 33778338›Full record

ArticleEnvironmental epidemiology (Philadelphia, Pa.)2019

Telomere length and socioeconomic status at neighborhood and individual levels among 80,000 adults in the Genetic Epidemiology Research on Adult Health and Aging cohort.

Stacey E Alexeeff, Catherine A Schaefer, Mark N Kvale, Jun Shan, Elizabeth H Blackburn, Neil Risch, Dilrini K Ranatunga, Eric Jorgenson, Thomas J Hoffmann, Lori C Sakoda and 2 more

Abstract read
In one paragraph

Article in Environmental epidemiology (Philadelphia, Pa.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  4. Impact of night shift work on telomere length and epigenetic age in older workers.Journal of occupational medicine and toxicology (London, England) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Stacey E AlexeeffDivision of Research, Oakland, Kaiser Permanente Northern California, Oakland, California.
Catherine A SchaeferDivision of Research, Oakland, Kaiser Permanente Northern California, Oakland, California.
Mark N KvaleUniversity of California San Francisco, San Francisco, California.
Jun ShanDivision of Research, Oakland, Kaiser Permanente Northern California, Oakland, California.
Elizabeth H BlackburnUniversity of California San Francisco, San Francisco, California.
Neil RischDivision of Research, Oakland, Kaiser Permanente Northern California, Oakland, California.
Dilrini K RanatungaDivision of Research, Oakland, Kaiser Permanente Northern California, Oakland, California.
Eric JorgensonDivision of Research, Oakland, Kaiser Permanente Northern California, Oakland, California.
Thomas J HoffmannUniversity of California San Francisco, San Francisco, California.
Lori C SakodaDivision of Research, Oakland, Kaiser Permanente Northern California, Oakland, California.
Charles P QuesenberryDivision of Research, Oakland, Kaiser Permanente Northern California, Oakland, California.
Stephen K Van Den EedenDivision of Research, Oakland, Kaiser Permanente Northern California, Oakland, California.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTelomere length (TL) may serve as a biologic marker of aging. We examined neighborhood and individual-level socioeconomic status (SES) in relation to TL.

methodsThe study included 84,996 non-Hispanic white subjects from the Genetic Epidemiology Research on Adult Health and Aging (GERA) cohort, part of the Research Program on Genes, Environment and Health. Relative TL (T/S) was log

resultsEach SD increase in NDI was associated with a decrease of 0.0192 in standardized TL, 95% confidence interval (CI) = -0.0306, -0.0078. There was no evidence of nonlinearity in the association of NDI with TL. We further found that less than high school education was associated with a decrease of 0.1371 in standardized TL, 95% CI = -0.1919, -0.0823 as compared to a college education. There were no differences in the associations by sex.

conclusionsWe found evidence that both lower neighborhood SES and lower individual-level SES are associated with shorter TL among non-Hispanic whites. Our findings suggest that socioeconomic factors may influence aging by contributing to shorter TL.

Indexed as

agingneighborhood factorssocioeconomic statustelomere length

Identifiers

PMID33778338
PMCPMC7939422

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.