Evidence map›Paper›PMID 33778156›Full record

ArticleRegenerative engineering and translational medicine2020

The Effects of Engineered Skeletal Muscle on Volumetric Muscle Loss in The Tibialis Anterior Of Rat After Three Months

Genevieve P Nutter, Keith W VanDusen, Shelby E Florida, Brian C Syverud, Lisa M Larkin

Open access · greenAbstract read
In one paragraph

Article in Regenerative engineering and translational medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Multifunctional scaffold based on TiMaterials today. Bio · 2026
    Article
  2. Review
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Genevieve P NutterDepartment of, Molecular & Integrative Physiology, University of Michigan, 2025 BSRB 109 Zina Pitcher Place, Ann Arbor, MI, 48109-2200.
Keith W VanDusenDepartment of, Molecular & Integrative Physiology, University of Michigan, 2025 BSRB 109 Zina Pitcher Place, Ann Arbor, MI, 48109-2200.
Shelby E FloridaDepartment of, Molecular & Integrative Physiology, University of Michigan, 2025 BSRB 109 Zina Pitcher Place, Ann Arbor, MI, 48109-2200.
Brian C SyverudDepartment of, Biomedical Engineering, University of Michigan, 2025 BSRB 109 Zina Pitcher Place, Ann Arbor, MI, 48109-2200.
Lisa M LarkinDepartment of, Molecular & Integrative Physiology, University of Michigan, 2025 BSRB 109 Zina Pitcher Place, Ann Arbor, MI, 48109-2200.
University of Michigan · US

Funding

Utilization of Engineered Skeletal Muscle Units to Repair Volumetric MuscleR01AR067744 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LARKIN, LISA M · 2015 to 2019
$2.3M
NIAMS NIH HHS R01 AR067744
6 · The paper itself

Abstract

Volumetric muscle loss (VML) is traumatic, degenerative, or surgical loss of skeletal muscle that exceeds the regenerative capacity of the remaining muscle, thus resulting in impaired muscle function. In humans, the loss of 30% or more mass of any one muscle will result in permanent structural and functional loss. Current VML repair treatments are limited by donor site morbidity and graft tissue availability, necessitating alternative muscle graft sources. To address this need, our lab has fabricated tissue-engineered skeletal muscle units (SMUs) for implantation into a 30 % VML model in the tibialis anterior (TA) muscle of rat. Previous results showed that after 28 days

Indexed as

nerve redirectsatellite cellscaffold-freeskeletal muscletissue engineeringvolumetric muscle loss

Identifiers

PMID33778156
PMCPMC7988939
OpenAlexW3088827683

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.