Evidence map›Paper›PMID 33778055›Full record

ArticleERJ open research2021

Cost-effectiveness analysis of a single-inhaler triple therapy for COPD in the UK.

Elisabeth Fenwick, Alan Martin, Melanie Schroeder, Stuart J Mealing, Oyinkansola Solanke, Nancy Risebrough, Afisi S Ismaila

Open access · goldAbstract read
In one paragraph

Article in ERJ open research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.8field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 19 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Economic Analysis of New Single-Inhaler Triple Therapies in Patients with COPD in the UK.International journal of chronic obstructive pulmonary disease · 2025
    Article
  6. Associations between the EQ-5D-5L and exacerbations of chronic obstructive pulmonary disease in the ETHOS trial.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Impact of COPD Exacerbations and Burden of Disease in Spain: AVOIDEX Study.International journal of chronic obstructive pulmonary disease · 2023
    Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Elisabeth FenwickICON Health Economics, ICON plc., Abingdon, UK.
Alan MartinValue Evidence and Outcomes, GlaxoSmithKline plc., Uxbridge, UK.
Melanie SchroederValue Evidence and Outcomes, GlaxoSmithKline plc., Brentford, UK.
Stuart J MealingICON Health Economics, ICON plc., Abingdon, UK.
Oyinkansola SolankeICON Health Economics, ICON plc., London, UK.
Nancy RisebroughICON Health Economics, ICON plc., Toronto, ON, Canada.
Afisi S IsmailaValue Evidence and Outcomes, GlaxoSmithKline plc., Collegeville, PA, USA.
GlaxoSmithKline (United Kingdom) · GBImperial Consultants · GBMcMaster University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

UK management costs for COPD, estimated at £1.9 billion/year, are rising. In the FULFIL (Lung Function and Quality of Life Assessment in Chronic Obstructive Pulmonary Disease with Closed Triple Therapy) study, single-inhaler triple therapy with fluticasone furoate/umeclidinium/vilanterol (100/62.5/25 µg) improved clinical outcomes

Identifiers

PMID33778055
PMCPMC7983252
OpenAlexW3112009581

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.