Evidence map›Paper›PMID 33777931›Full record

ArticleFrontiers in cell and developmental biology2021

The Interaction Efficiency of XPD-p44 With Bulky DNA Damages Depends on the Structure of the Damage.

Irina Petruseva, Natalia Naumenko, Jochen Kuper, Rashid Anarbaev, Jeannette Kappenberger, Caroline Kisker, Olga Lavrik

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Irina PetrusevaLaboratory of Bioorganic Chemistry of Enzymes, Institute of Chemical Biology and Fundamental Medicine SB RAS, Novosibirsk, Russia.
Natalia NaumenkoLaboratory of Bioorganic Chemistry of Enzymes, Institute of Chemical Biology and Fundamental Medicine SB RAS, Novosibirsk, Russia.
Jochen KuperRudolf Virchow Center for Integrative and Translational Bioimaging, University of Wuerzburg, Wuerzburg, Germany.
Rashid AnarbaevLaboratory of Bioorganic Chemistry of Enzymes, Institute of Chemical Biology and Fundamental Medicine SB RAS, Novosibirsk, Russia.
Jeannette KappenbergerRudolf Virchow Center for Integrative and Translational Bioimaging, University of Wuerzburg, Wuerzburg, Germany.
Caroline KiskerRudolf Virchow Center for Integrative and Translational Bioimaging, University of Wuerzburg, Wuerzburg, Germany.
Olga LavrikLaboratory of Bioorganic Chemistry of Enzymes, Institute of Chemical Biology and Fundamental Medicine SB RAS, Novosibirsk, Russia.
Institute of Chemical Biology and Fundamental Medicine · RUUniversity of Würzburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The successful elimination of bulky DNA damages via the nucleotide excision repair (NER) system is largely determined by the damage recognition step. This step consists of primary recognition and verification of the damage. The TFIIH helicase XPD plays a key role in the verification step during NER. To date, the mechanism of damage verification is not sufficiently understood and requires further detailed research. This study is a systematic investigation of the interaction of ctXPD

Indexed as

bulky damages recognitionDNA damagenucleotide excision repairphoto-cross-linkingprotein-DNA interactionXPD helicase

Identifiers

PMID33777931
PMCPMC7991749
OpenAlexW3134683065

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.