Evidence map›Paper›PMID 33777910›Full record

ArticleFrontiers in bioengineering and biotechnology2021

Balance Impairments as Differential Markers of Dementia Disease Subtype.

Ríona Mc Ardle, Stephanie Pratt, Christopher Buckley, Silvia Del Din, Brook Galna, Alan Thomas, Lynn Rochester, Lisa Alcock

Open access · goldAbstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
5.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Ríona Mc ArdleTranslational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
Stephanie PrattTranslational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
Christopher BuckleyDepartment of Sport, Exercise and Rehabilitation, Northumbria University, Newcastle upon Tyne, United Kingdom.
Silvia Del DinTranslational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
Brook GalnaSchool of Biomedical, Nutritional and Sports Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom.
Alan ThomasTranslational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
Lynn RochesterTranslational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
Lisa AlcockTranslational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
Newcastle University · GBNational Health Service · GBNorthumbria University · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

backgroundAccurately differentiating dementia subtypes, such as Alzheimer's disease (AD) and Lewy body disease [including dementia with Lewy bodies (DLB) and Parkinson's disease dementia (PDD)] is important to ensure appropriate management and treatment of the disease. Similarities in clinical presentation create difficulties for differential diagnosis. Simple supportive markers, such as balance assessments, may be useful to the diagnostic toolkit. This study aimed to identify differences in balance impairments between different dementia disease subtypes and normal aging using a single triaxial accelerometer.

methodsNinety-seven participants were recruited, forming four groups: cognitive impairment due to Alzheimer's disease (AD group;

resultsThe PDD group demonstrated higher RMS [combined ( DISCUSSION: Although feasible and quick to conduct, key findings suggest that an accelerometer-based balance during quiet standing does not differentiate dementia disease subtypes accurately. Assessments that challenge balance more, such as gait or standing with eyes closed, may prove more effective to support differential diagnosis.

Indexed as

accelerometerAlzheimer’s diseasebalancedementiaLewy body diseaseParkinson’s diseasepostural control

Identifiers

PMID33777910
PMCPMC7991998
OpenAlexW3127548248

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.