Evidence map›Paper›PMID 33777907›Full record

ReviewFrontiers in bioengineering and biotechnology2021

Metal-Organic Framework (MOF)-Based Biomaterials for Tissue Engineering and Regenerative Medicine.

Moldir Shyngys, Jia Ren, Xiaoqi Liang, Jiechen Miao, Anna Blocki, Sebastian Beyer

Abstract readReview
In one paragraph

Review in Frontiers in bioengineering and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Engineering the Immune Response to Biomaterials.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  12. Article
  13. Review
  14. Review
  15. Application and progress of 3D printed biomaterials in osteoporosis.Frontiers in bioengineering and biotechnology · 2025
    Review
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Moldir ShyngysDepartment of Biomedical Engineering, The Chinese University of Hong Kong, Shatin, Hong Kong.
Jia RenDepartment of Biomedical Engineering, The Chinese University of Hong Kong, Shatin, Hong Kong.
Xiaoqi LiangDepartment of Biomedical Engineering, The Chinese University of Hong Kong, Shatin, Hong Kong.
Jiechen MiaoDepartment of Biomedical Engineering, The Chinese University of Hong Kong, Shatin, Hong Kong.
Anna BlockiInstitute for Tissue Engineering & Regenerative Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong.
Sebastian BeyerDepartment of Biomedical Engineering, The Chinese University of Hong Kong, Shatin, Hong Kong.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The synthesis of Metal-organic Frameworks (MOFs) and their evaluation for various applications is one of the largest research areas within materials sciences and chemistry. Here, the use of MOFs in biomaterials and implants is summarized as narrative review addressing primarely the Tissue Engineering and Regenerative Medicine (TERM) community. Focus is given on MOFs as bioactive component to aid tissue engineering and to augment clinically established or future therapies in regenerative medicine. A summary of synthesis methods suitable for TERM laboratories and key properties of MOFs relevant to biomaterials is provided. The use of MOFs is categorized according to their targeted organ (bone, cardio-vascular, skin and nervous tissue) and whether the MOFs are used as intrinsically bioactive material or as drug delivery vehicle. Further distinction between

Indexed as

biomaterialbonecardio-vascularmetal-organic frameworksnervous tissueregenerative medicinetissue engineering

Identifiers

PMID33777907
PMCPMC7991400

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.