Evidence map›Paper›PMID 33777837›Full record

ReviewFrontiers in cellular and infection microbiology2021

Interferons: Tug of War Between Bacteria and Their Host.

Noémie Alphonse, Ruth E Dickenson, Charlotte Odendall

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
  2. Article
  3. The strategies and advances of mRNA translation booster.Asian journal of pharmaceutical sciences · 2025
    Review
  4. Article
  5. Review
  6. Article
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  11. Review
  12. Article
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  14. Article
  15. Article
  16. Immunomodulatory Role of Interferons in Viral and Bacterial Infections.International journal of molecular sciences · 2023
    Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Noémie AlphonseDepartment of Infectious Diseases, School of Immunology and Microbial Sciences, King's College London, London, United Kingdom.
Ruth E DickensonDepartment of Infectious Diseases, School of Immunology and Microbial Sciences, King's College London, London, United Kingdom.
Charlotte OdendallDepartment of Infectious Diseases, School of Immunology and Microbial Sciences, King's College London, London, United Kingdom.
King's College London · GBThe Francis Crick Institute · GB

Funding

Cancer Research UKMedical Research CouncilWellcome TrustWellcome Trust 206200/Z/17/ZWellcome Trust FC001206
6 · The paper itself

Abstract

Type I and III interferons (IFNs) are archetypally antiviral cytokines that are induced in response to recognition of foreign material by pattern recognition receptors (PRRs). Though their roles in anti-viral immunity are well established, recent evidence suggests that they are also crucial mediators of inflammatory processes during bacterial infections. Type I and III IFNs restrict bacterial infection

Indexed as

Antiviral AgentsInterferonsBacteriaImmunity, InnateReceptors, Pattern RecognitionSignal TransductionAntiviral AgentsInterferonsReceptors, Pattern Recognitionbacterial effectorshost-pathogen interactionsimmunityinterferonsinterferon-stimulated genesjanus kinase signal transducer and activator of transcription signalingmicrobial pathogenesis

Identifiers

PMID33777837
PMCPMC7988231
OpenAlexW3135205896

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.