Evidence map›Paper›PMID 33777807›Full record

ArticleFrontiers in oncology2021

Defining the Optimal Method for Measuring Metabolic Tumor Volume on Preoperative

Yasuko Tatewaki, Chiaki Maeda Terao, Kyohei Ariake, Ryoko Saito, Tatsushi Mutoh, Hideo Shimomura, Fuyuhiko Motoi, Masamichi Mizuma, Hayato Odagiri, Michiaki Unno and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Nuclear medicine and molecular imaging · 2025
    Article
  2. Article
  3. Scientific reports · 2025
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Yasuko TatewakiDepartment of Nuclear Medicine and Radiology, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan.
Chiaki Maeda TeraoDepartment of Nuclear Medicine and Radiology, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan.
Kyohei AriakeDepartment of Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan.
Ryoko SaitoDepartment of Pathology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Tatsushi MutohDepartment of Nuclear Medicine and Radiology, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan.
Hideo ShimomuraDepartment of Nuclear Medicine and Radiology, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan.
Fuyuhiko MotoiDepartment of Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan.
Masamichi MizumaDepartment of Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan.
Hayato OdagiriDivision of Radiology, Tohoku University Hospital, Sendai, Japan.
Michiaki UnnoDepartment of Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan.
Yasuyuki TakiDepartment of Nuclear Medicine and Radiology, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan.
Tohoku University · JPTohoku University Hospital · JPSendai Kousei Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesMetabolic tumor volume (MTV) on

methodsSeventy-three patients with resected PDAC who underwent

resultsIn receiver operating characteristic curve analysis, MTV by the fixed-absolute threshold method based on a threshold value of 3.5 (MTV3.5) performed best in our study with area under the curve 0.724, sensitivity of 65%, and specificity of 75%. In univariate and multivariate analyses, MTV3.5 was significantly associated with disease-specific and recurrence-free survival.

conclusionsMTV3.5 by absolute threshold on pre-treatment FDG-PET/CT was the best independent prognostic predictor in resectable PDAC compared with other absolute threshold values and relative threshold values.

Indexed as

FDG PET = F-18 fluorodeoxyglucose positron emission tomographymetabolic tumor volume (MTV)PDAC=pancreatic ductal adenocarcinomaprognosisthreshold

Identifiers

PMID33777807
PMCPMC7994512
OpenAlexW3136844990

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.