Evidence map›Paper›PMID 33777759›Full record

ArticleFrontiers in oncology2021

Initial Clinical Experience of MR-Guided Radiotherapy for Non-Small Cell Lung Cancer.

Cathryn B Crockett, Pamela Samson, Robert Chuter, Michael Dubec, Corinne Faivre-Finn, Olga L Green, Sara L Hackett, Fiona McDonald, Clifford Robinson, Anna-Maria Shiarli and 5 more

Abstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
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  6. Magnetic Resonance Imaging Sequences and Technologies in Adaptive Radiation Therapy.International journal of radiation oncology, biology, physics · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Cathryn B CrockettRadiotherapy Related Research, The Christie NHS Foundation Trust, Manchester, United Kingdom.
Pamela SamsonDepartment of Radiation Oncology, Washington University in St. Louis, St. Louis, MO, United States.
Robert ChuterRadiotherapy Related Research, The Christie NHS Foundation Trust, Manchester, United Kingdom.
Michael DubecRadiotherapy Related Research, The Christie NHS Foundation Trust, Manchester, United Kingdom.
Corinne Faivre-FinnRadiotherapy Related Research, The Christie NHS Foundation Trust, Manchester, United Kingdom.
Olga L GreenDepartment of Radiation Oncology, Washington University in St. Louis, St. Louis, MO, United States.
Sara L HackettDepartment of Radiation Oncology, University Medical Center Utrecht, Utrecht, Netherlands.
Fiona McDonaldDepartment of Radiotherapy, Royal Marsden NHS Foundation Trust, London, United Kingdom.
Clifford RobinsonDepartment of Radiation Oncology, Washington University in St. Louis, St. Louis, MO, United States.
Anna-Maria ShiarliDepartment of Radiotherapy, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.
Michael W StrazaDepartment of Radiation Oncology, Froedtert and the Medical College of Wisconsin, Milwaukee, WI, United States.
Joost J C VerhoeffDepartment of Radiation Oncology, University Medical Center Utrecht, Utrecht, Netherlands.
Maria Werner-WasikDepartment of Radiation Oncology, Sidney Kimmel Cancer Center at Thomas Jefferson University, Philadelphia, PA, United States.
Gregory VlacichDepartment of Radiation Oncology, Washington University in St. Louis, St. Louis, MO, United States.
David CobbenRadiotherapy Related Research, The Christie NHS Foundation Trust, Manchester, United Kingdom.

Funding

Cancer Research UK 21993
6 · The paper itself

Abstract

Curative-intent radiotherapy plays an integral role in the treatment of lung cancer and therefore improving its therapeutic index is vital. MR guided radiotherapy (MRgRT) systems are the latest technological advance which may help with achieving this aim. The majority of MRgRT treatments delivered to date have been stereotactic body radiation therapy (SBRT) based and include the treatment of (ultra-) central tumors. However, there is a move to also implement MRgRT as curative-intent treatment for patients with inoperable locally advanced NSCLC. This paper presents the initial clinical experience of using the two commercially available systems to date: the ViewRay MRIdian and Elekta Unity. The challenges and potential solutions associated with MRgRT in lung cancer will also be highlighted.

Indexed as

adaptiveexternal beam radiotherapyimage-guided radiotherapy (IGRT)magnetic resonance imaging (MRI)MR-guided radiotherapy (MRgRT)non-small cell lung cancer (NSCLC)stereotactic body radiation therapy (SBRT)

Identifiers

PMID33777759
PMCPMC7988221

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.