Evidence map›Paper›PMID 33777731›Full record

ArticleFrontiers in oncology2021

Junctional Adhesion Molecule-Like Protein Promotes Tumor Progression and Metastasis

Yuying Fang, Jianmin Yang, Guohong Zu, Changsheng Cong, Shuai Liu, Fei Xue, Shuzhen Ma, Jie Liu, Yuping Sun, Meili Sun

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
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  5. Dexamethasone-Induced MerTKJournal of genomics · 2025
    Article
  6. Review
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  15. The Roles of Junctional Adhesion Molecules (JAMs) in Cell Migration.Frontiers in cell and developmental biology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Yuying FangDepartment of Oncology, Jinan Central Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Jianmin YangThe Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese Ministry of Health and Chinese Academy of Medical Sciences, The State and Shandong Province Joint Key Laboratory of Translational Cardiovascular Medicine, Department of Cardiology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Guohong ZuDepartment of Oncology, Jinan Central Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Changsheng CongDepartment of Oncology, Jinan Central Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Shuai LiuDepartment of Oncology, Jinan Central Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Fei XueThe Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese Ministry of Health and Chinese Academy of Medical Sciences, The State and Shandong Province Joint Key Laboratory of Translational Cardiovascular Medicine, Department of Cardiology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Shuzhen MaDepartment of Oncology, Jinan Central Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Jie LiuDepartment of Oncology, Jinan Central Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Yuping SunDepartment of Oncology, Jinan Central Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Meili SunDepartment of Oncology, Jinan Central Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Shandong University · CNShandong First Medical University · CNJinan Central Hospital · CNChinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Junctional adhesion molecule-like protein (JAML), a newly discovered junctional adhesion molecule (JAM), mediates the adhesion and migration processes of various immune cells and endothelial/epithelial cells, ultimately regulating inflammation reaction. However, its role in tumors remains to be determined. The expression of JAML was examined in gastric cancer (GC) and peritumoral tissues from 63 patients. The relationship between JAML expression and clinical characteristics was also observed.

Indexed as

gastric cancerjunctional adhesion molecule-like protein (JAML)migrationp38tumor progression

Identifiers

PMID33777731
PMCPMC7991718
OpenAlexW3134425949

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.