Evidence map›Paper›PMID 33777718›Full record

ArticlePublic health action2021

Trends in extrapulmonary TB cases at three teaching hospitals in Ghana, 2008-2017.

S O Addo, G I Mensah, L Mosi, A Abrahams, B Bonfoh, R Kazwala, J Zinsstag, K K Addo

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Article in Public health action, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

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5citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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5 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

S O AddoDepartment of Bacteriology, Noguchi Memorial Institute for Medical Research, College of Health Sciences, University of Ghana, Accra, Ghana.
G I MensahDepartment of Bacteriology, Noguchi Memorial Institute for Medical Research, College of Health Sciences, University of Ghana, Accra, Ghana.
L MosiDepartment of Biochemistry, Cell and Molecular Biology, College of Basic and Applied Sciences, University of Ghana, Accra, Ghana.
A AbrahamsDepartment of Pathology, University of Ghana Medical School, College of Health Sciences, University of Ghana, Accra, Ghana.
B BonfohCentre Suisse de Recherches Scientifique en Cote d'Ivoire, Abidjan, Cote d'Ivoire.
R KazwalaDepartment of Veterinary Medicine and Public Health, Sokoine University of Agriculture, Morogoro, Tanzania.
J ZinsstagDepartment of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland.
K K AddoDepartment of Bacteriology, Noguchi Memorial Institute for Medical Research, College of Health Sciences, University of Ghana, Accra, Ghana.

Funding

EPA EP-C-15-008Wellcome Trust
6 · The paper itself

Abstract

settingThree teaching hospitals in Ghana.

objectiveTo elucidate trends in demographics, clinical characteristics and treatment outcomes in extrapulmonary TB (EPTB) patients.

designThis was a retrospective study involving the review and comparison of EPTB and pulmonary TB (PTB) data from 1 January 2008 to 31 December 2017 in TB registers and treatment cards.

resultsOf 15,392 TB cases, 4607 (30%) were EPTB, including 4477/4607 (97%) new cases. There were 2,679/4607 (58%) males and the age range was 0.3 to 96 years. Pleural TB (1021/4607, 22%) was the most common. Treatment success rates for EPTB and PTB were respectively 72% and 84%. HIV positivity was high among patients with disseminated/miliary TB (429/779, 55%) and TB meningitis (242/526, 46%). To note, disseminated/miliary TB (χ

conclusionsThere is male preponderance for both EPTB and PTB in Ghana. Increasing age, disseminated/ miliary TB, TB meningitis and HIV are risk factors for mortality among EPTB patients. This emphasises the need for public education on the risk factors for EPTB and preventive strategies.

Indexed as

EPTBretrospective studyTB registertreatment outcomes

Identifiers

PMID33777718
PMCPMC7987251

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