Evidence map›Paper›PMID 33777715›Full record

ArticlePublic health action2021

Evaluating the availability of essential drugs for hypertension, diabetes and asthma in rural Rwanda, 2018.

F Mbonyinshuti, K C Takarinda, S Ade, M Manzi, P G Iradukunda, J Kabatende, T Habiyaremye, P C Kayumba

Open access · diamondAbstract read
In one paragraph

Article in Public health action, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 7 countries.

F MbonyinshutiHuman Resource for Health Secretariat, Ministry of Health, Kigali, Rwanda.
K C TakarindaInternational Union Against Tuberculosis and Lung Disease, Paris, France.
S AdeInternational Union Against Tuberculosis and Lung Disease, Paris, France.
M ManziMedical Department, Médecins Sans Frontières, Operational Centre Brussels, MSF-Luxembourg (LuxOR), Luxembourg, Belgium.
P G IradukundaRwanda Food and Drugs Authority, Kigali, Rwanda.
J KabatendeRwanda Food and Drugs Authority, Kigali, Rwanda.
T HabiyaremyeHuman Resource for Health Secretariat, Ministry of Health, Kigali, Rwanda.
P C KayumbaCollege of Business and Economics, African Centre of Excellence in Data Science, University of Rwanda, Kigali, Rwanda.
Rwanda Biomedical Center · RWRwanda Development Board · RWInternational Union Against Tuberculosis and Lung Disease · FRMédecins Sans Frontières · LUMinistry of Health and Child Welfare · ZWUniversity of Rwanda · RW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

settingHypertension, diabetes mellitus and asthma are on the rise in developing countries, including Rwanda; there is thus a need to ensure uninterrupted drug availability.

objectivesTo assess 1) the frequency and duration of drug stock-outs; 2) lead time duration 3) monthly stock levels; and 4) drug quantities requested vs. quantity delivered for captopril, metformin and inhaled salbutamol between January and December 2018 Kirehe District, Rwanda.

designThis was a cross-sectional study using secondary programme data.

resultsThe median annual stock-outs for captopril, metformin and inhaled salbutamol were respectively 4 (IQR 3-4), 3 (IQR 2-3) and 4 (IQR 4-5) at rural health facilities (RHCs); no stock-outs occurred at the district hospital. For all three drugs, the median lead time was 7.5 days (IQR 5.5-11.5) at the hospital vs. 5 days (IQR 3-6) in RHCs. Stock status for captopril was below the 4-week minimum stock level for 2/12 months at the hospital vs. 7/12 months at the RHCs, while metformin and inhaled salbutamol were below the 4-week minimum stock levels for respectively 1/12 and 4/12 months at both hospital and RHCs. Total drug quantities delivered were less than the combined total quantities requested in respectively 8/12, 5/12 and 8/12 months for captopril, metformin and inhaled salbutamol.

conclusionThere is a need to regularly and effectively monitor drug stock levels and ensure timely and sufficient stock replenishment to avert stock-outs.

Indexed as

non-communicable diseasesoperational researchRwandaSORT ITsupply chain

Identifiers

PMID33777715
PMCPMC7987247
OpenAlexW3138779139

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.