ArticleActa pharmaceutica Sinica. B2021
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Article in Acta pharmaceutica Sinica. B, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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0cells of the map it votes in
21citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 59 citations in OpenAlex.
- Molecular Mechanistic Pathways Targeted by Natural Products in the Prevention and Treatment of Alcoholic Liver Disease.Life (Basel, Switzerland) · 2026Review
- A novel Kupffer cell-targeting nanoparticle system to Mitigate alcohol-associated liver disease.Biomaterials · 2026Article
- Mitochondria as a Therapeutic Target in Metabolic Disorders.Mini reviews in medicinal chemistry · 2026Review
- Knockout of IGFBP3 improves alcohol-induced liver injury via Akt/GSK3β and TMEM219/caspase 8 pathways.Frontiers in physiology · 2026Article
- Cracking the Sulfur Code: Garlic Bioactive Molecules as Multi-Target Blueprints for Drug Discovery.Pharmaceuticals (Basel, Switzerland) · 2025Review
- Heart-guarding or heart-harming? The dual role of epicardial adipose tissue in cardiovascular health and disease.International journal of obesity (2005) · 2025Review
- Chronic Intermittent Low-Pressure Hypoxia Suppresses Inflammation and Regulates Glycolipids by Modulating Mitochondrial Respiration in db/db Mice.Metabolites · 2025Article
- Association between AIP and incident T2DM in patients with NAFLD: a retrospective study.BMC endocrine disorders · 2025Article
- High-content screening identifies ganoderic acid A as a senotherapeutic to prevent cellular senescence and extend healthspan in preclinical models.Nature communications · 2025Article
- Chronic alcohol intake disrupts cytochrome P450 enzyme activity in alcoholic fatty liver disease: insights into metabolic alterations and therapeutic targets.Frontiers in chemistry · 2025Article
- Review
- Exploring the therapeutic potential of garlic in alcoholic liver disease: a network pharmacology and experimental validation study.Genes & nutrition · 2024Article
- The association between triglyceride-glucose index and the likelihood of cardiovascular disease in the U.S. population of older adults aged ≥ 60 years: a population-based study.Cardiovascular diabetology · 2024Article
- Psychochemical changes and functional properties of organosulfur and polysaccharide compounds of black garlic (Current research in food science · 2024Review
- UHRF1/DNMT1-MZF1 axis-modulated intragenic site-specific CpGI methylation confers divergent expression and opposing functions ofActa pharmaceutica Sinica. B · 2023Article
- Melatonin alleviates alcoholic liver diseaseActa pharmaceutica Sinica. B · 2023Article
- Polydeoxyribonucleotide ameliorates alcoholic liver injury though suppressing phosphatidylinositol 3-kinase/protein kinase B signaling pathway in mice.Journal of exercise rehabilitation · 2022Article
- Inhibition of Hepatic AMPK Pathway Contributes to Free Fatty Acids-Induced Fatty Liver Disease in Laying Hen.Metabolites · 2022Article
- Icariside II Exerts Anti-Type 2 Diabetic Effect by Targeting PPARα/γ: Involvement of ROS/NF-κB/IRS1 Signaling Pathway.Antioxidants (Basel, Switzerland) · 2022Article
- Mechanism exploration of Gouqi-wentang formula against type 2 diabetes mellitus by phytochemistry and network pharmacology-based analysis and biological validation.Chinese medicine · 2021Article
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 3 countries.
Pingping LuoClinical Medicine Research Institute, the First Affiliated Hospital of Jinan University, Guangzhou 510632, China.
Ming ZhengDepartment of Interventional Surgery, the First Affiliated Hospital of Jinan University, Guangzhou 510632, China.
Rui ZhangClinical Medicine Research Institute, the First Affiliated Hospital of Jinan University, Guangzhou 510632, China.
Hong ZhangDepartment of Interventional Surgery, the First Affiliated Hospital of Jinan University, Guangzhou 510632, China.
Yingxia LiuState Key Discipline of Infectious Diseases, Department of Infectious Diseases, Shenzhen Third People's Hospital, Shenzhen 518000, China.
Wei LiFaculty of Pharmaceutical Sciences, Toho University, Chiba 2748510, Japan.
Xiaoming SunSchool of Integrative Pharmacy, Institute of Integrative Pharmaceutical Research, Guangdong Pharmaceutical University, Guangzhou 510000, China.
Qian YuSchool of Biomedical Sciences, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Hong Kong 999077, China.
George L TipoeSchool of Biomedical Sciences, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Hong Kong 999077, China.
Jia XiaoClinical Medicine Research Institute, the First Affiliated Hospital of Jinan University, Guangzhou 510632, China.
First Affiliated Hospital of Jinan University · CNUniversity of Hong Kong · HKGuangdong Pharmaceutical University · CNShenzhen Third People’s Hospital · CNToho University · JP
Funding
No grant is acknowledged in the PubMed record.
Abstract
Alcoholic liver disease (ALD) causes insulin resistance, lipid metabolism dysfunction, and inflammation. We investigated the protective effects and direct regulating target of
Indexed as
ADIPOQ, adiponectinAKTAlcoholic liver diseaseALD, alcoholic liver diseaseALDH2, aldehyde dehydrogenase 2ALT, alanine aminotransferaseAMPK, adenosine 5′-monophosphate (AMP)-activated protein kinaseAST, aspartate aminotransferaseATGL, adipose triglyceride lipaseCPT1, carnitine palmitoyltransferase ICYP2E1, cytochrome P450 2E1FDA, U.S. Food and Drug AdministrationFFA, free fatty acidsGRB14, growth factor receptor-bound protein 14GSK3βGSK3β, glycogen synthase kinase 3 betaGTT, glucose tolerance testHSL, hormone sensitive lipaseIGF-1, insulin-like growth factors-1IL, interleukinINSR, insulin receptorInsulin receptorInsulin resistanceIRS-1IRS, insulin receptor substrateIRTK, insulin receptor tyrosine kinaseLDLR, low-density lipoprotein receptorLRP6, low-density lipoprotein receptor related protein 6MTT, 3-(4,5-dimethyl-thiazol-2-yl)-2,5-diphenyl-tetrazolium bromideNAC, N-acetyl-cysteineNAFLD, non-alcoholic fatty liver diseaseNAS, NAFLD activity scoreNF-κB, nuclear factor kappa BNIAAA, National Institute on Alcohol Abuse and AlcoholismNRF2, nuclear factor erythroid 2-related factor 2ORF, open reading framePA, palmitate acidPPARα, peroxisome proliferator-activated receptor alphaRER, respiratory exchange ratioSafetyS-AllylmercaptocysteineSAMC, S-allylmercaptocysteineSPR, surface plasmon resonanceSREBP-1c, sterol regulatory element-binding protein 1cTCF/LEF, T-cell factor/lymphoid enhancer factorTC, total cholesterolTG, triglycerideTNF, tumor necrosis factorTSA, thermal shift assayWAT, white adipose tissuesWT, wild-type
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.