Evidence map›Paper›PMID 33777521›Full record

ArticlePeerJ2021

Reproducible, portable, and efficient ancient genome reconstruction with nf-core/eager.

James A Fellows Yates, Thiseas C Lamnidis, Maxime Borry, Aida Andrades Valtueña, Zandra Fagernäs, Stephen Clayton, Maxime U Garcia, Judith Neukamm, Alexander Peltzer

Abstract read
In one paragraph

Article in PeerJ, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers.

0numbers the graph read from it
0cells of the map it votes in
77citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

77 citing papers in PubMed.

  1. Article
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  3. The Oral Microbiome of King Richard III of England.American journal of biological anthropology · 2026
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17 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

James A Fellows YatesDepartment of Archaeogenetics, Max Planck Institute for the Science of Human History, Jena, Germany.
Thiseas C LamnidisDepartment of Archaeogenetics, Max Planck Institute for the Science of Human History, Jena, Germany.
Maxime BorryDepartment of Archaeogenetics, Max Planck Institute for the Science of Human History, Jena, Germany.
Aida Andrades ValtueñaDepartment of Archaeogenetics, Max Planck Institute for the Science of Human History, Jena, Germany.
Zandra FagernäsDepartment of Archaeogenetics, Max Planck Institute for the Science of Human History, Jena, Germany.
Stephen ClaytonDepartment of Archaeogenetics, Max Planck Institute for the Science of Human History, Jena, Germany.
Maxime U GarciaNational Genomics Infrastructure, Science for Life Laboratory, Stockholm, Sweden.
Judith NeukammInstitute of Evolutionary Medicine, University of Zurich, Zurich, Switzerland.
Alexander PeltzerDepartment of Archaeogenetics, Max Planck Institute for the Science of Human History, Jena, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The broadening utilisation of ancient DNA to address archaeological, palaeontological, and biological questions is resulting in a rising diversity in the size of laboratories and scale of analyses being performed. In the context of this heterogeneous landscape, we present an advanced, and entirely redesigned and extended version of the EAGER pipeline for the analysis of ancient genomic data. This Nextflow pipeline aims to address three main themes: accessibility and adaptability to different computing configurations, reproducibility to ensure robust analytical standards, and updating the pipeline to the latest routine ancient genomic practices. The new version of EAGER has been developed within the nf-core initiative to ensure high-quality software development and maintenance support; contributing to a long-term life-cycle for the pipeline. nf-core/eager will assist in ensuring that a wider range of ancient DNA analyses can be applied by a diverse range of research groups and fields.

Indexed as

Ancient DNABioinformaticsGenomicsMetagenomicsNextflowPalaeogenomicsPipelineReproducibility

Identifiers

PMID33777521
PMCPMC7977378

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.