Evidence map›Paper›PMID 33777498›Full record

ArticleTremor and other hyperkinetic movements (New York, N.Y.)2021

Tardive Blepharospasm May Respond to Bilateral Pallidal Deep Brain Stimulation.

Virgilio Gerald H Evidente, Francisco A Ponce, Maris H Evidente, Margaret Lambert, Robin Garrett

Abstract readCase Reports
In one paragraph

Article in Tremor and other hyperkinetic movements (New York, N.Y.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Virgilio Gerald H EvidenteMovement Disorder Center of Arizona, Scottsdale, AZ, US.ORCID 0000-0001-6341-6933
Francisco A PonceBarrow Neurological Institute, Phoenix, AZ, US.ORCID 0000-0001-5240-0207
Maris H EvidenteMovement Disorder Center of Arizona, Scottsdale, AZ, US.
Margaret LambertMovement Disorder Center of Arizona, Scottsdale, AZ, US.
Robin GarrettMovement Disorder Center of Arizona, Scottsdale, AZ, US.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: To date, there have been no reports of tardive blepharospasm being treated with deep brain stimulation (DBS), though there have been two reports of focal blepharospasm responding favorably to bilateral pallidal DBS. Case: A 34 year old man with tardive blepharospasm that was refractory to oral medications as well as botulinum toxin types A and B underwent bilateral pallidal DBS under general anesthesia. He had significant improvement of his severe blepharospasm by one and half months post-DBS which was sustained at last follow-up 30 months post-DBS. The best programming parameters included pulse widths of 90-100 µsec, frequencies of 140-150 Hz, and stimulating the ventral contacts in each side. Conclusion: Our case represents the first report of medically refractory tardive blepharospasm responding favorably to bilateral pallidal DBS.

Indexed as

BlepharospasmDeep Brain StimulationAdultGlobus PallidusHumansMaleTreatment OutcomeBlepharospasmDBSdeep brain stimulationGPipallidal DBSTardive

Identifiers

PMID33777498
PMCPMC7977745

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.